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Discovery of stimulation-responsive immune enhancers with CRISPR activation.
Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A. Simeonov DR, et al. Among authors: greenleaf wj. Nature. 2017 Sep 7;549(7670):111-115. doi: 10.1038/nature23875. Epub 2017 Aug 30. Nature. 2017. PMID: 28854172 Free PMC article.
Chromatin accessibility and the regulatory epigenome.
Klemm SL, Shipony Z, Greenleaf WJ. Klemm SL, et al. Among authors: greenleaf wj. Nat Rev Genet. 2019 Apr;20(4):207-220. doi: 10.1038/s41576-018-0089-8. Nat Rev Genet. 2019. PMID: 30675018 Review.
Long-range single-molecule mapping of chromatin accessibility in eukaryotes.
Shipony Z, Marinov GK, Swaffer MP, Sinnott-Armstrong NA, Skotheim JM, Kundaje A, Greenleaf WJ. Shipony Z, et al. Among authors: greenleaf wj. Nat Methods. 2020 Mar;17(3):319-327. doi: 10.1038/s41592-019-0730-2. Epub 2020 Feb 10. Nat Methods. 2020. PMID: 32042188 Free PMC article.
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19.
Wilk AJ, Lee MJ, Wei B, Parks B, Pi R, Martínez-Colón GJ, Ranganath T, Zhao NQ, Taylor S, Becker W; Stanford COVID-19 Biobank; Jimenez-Morales D, Blomkalns AL, O'Hara R, Ashley EA, Nadeau KC, Yang S, Holmes S, Rabinovitch M, Rogers AJ, Greenleaf WJ, Blish CA. Wilk AJ, et al. Among authors: greenleaf wj. J Exp Med. 2021 Aug 2;218(8):e20210582. doi: 10.1084/jem.20210582. Epub 2021 Jun 15. J Exp Med. 2021. PMID: 34128959 Free PMC article.
194 results