Qiu L - Search Results

1

Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer.

Qiu L, Jiang H, Cho K, Yu Y, Jones LA, Huang T, Perlmutter JS, Gropler RJ, Brier MR, Patti GJ, Benzinger TLS, Tu Z. Qiu L, et al. ACS Chem Neurosci. 2024 May 1;15(9):1882-1892. doi: 10.1021/acschemneuro.4c00077. Epub 2024 Apr 18. ACS Chem Neurosci. 2024. PMID: 38634759

2

Synthesis and in vitro evaluation of new TRPV4 ligands and biodistribution study of an ¹¹C-labeled radiotracer in rodents.

Qiu L, Du L, Liang Q, Hu H, Tu Z. Qiu L, et al. Bioorg Med Chem Lett. 2020 Nov 15;30(22):127573. doi: 10.1016/j.bmcl.2020.127573. Epub 2020 Sep 24. Bioorg Med Chem Lett. 2020. PMID: 32980513 Free PMC article.

3

InVitro and In Vivo Investigation of S1PR1 Expression in the Central Nervous System Using [³H]CS1P1 and [¹¹C]CS1P1.

Jiang H, Joshi S, Liu H, Mansor S, Qiu L, Zhao H, Whitehead T, Gropler RJ, Wu GF, Cross AH, Benzinger TLS, Shoghi KI, Perlmutter JS, Tu Z. Jiang H, et al. Among authors: qiu l. ACS Chem Neurosci. 2021 Oct 6;12(19):3733-3744. doi: 10.1021/acschemneuro.1c00492. Epub 2021 Sep 13. ACS Chem Neurosci. 2021. PMID: 34516079 Free PMC article.

4

Radiosynthesis and evaluation of a fluorine-18 radiotracer [¹⁸F]FS1P1 for imaging sphingosine-1-phosphate receptor 1.

Qiu L, Jiang H, Yu Y, Gu J, Wang J, Zhao H, Huang T, Gropler RJ, Klein RS, Perlmutter JS, Tu Z. Qiu L, et al. Org Biomol Chem. 2022 Feb 2;20(5):1041-1052. doi: 10.1039/d1ob02225c. Org Biomol Chem. 2022. PMID: 35029272 Free PMC article.

5

Radiosynthesis and Evaluation of a C-11 Radiotracer for Transient Receptor Potential Canonical 5 in the Brain.

Yu Y, Jiang H, Liang Q, Qiu L, Huang T, Hu H, Bolshakov VY, Perlmutter JS, Tu Z. Yu Y, et al. Among authors: qiu l. Mol Imaging Biol. 2023 Apr;25(2):334-342. doi: 10.1007/s11307-022-01760-y. Epub 2022 Aug 11. Mol Imaging Biol. 2023. PMID: 35951211 Free PMC article.

6

Discovery of a Promising Fluorine-18 Positron Emission Tomography Radiotracer for Imaging Sphingosine-1-Phosphate Receptor 1 in the Brain.

Qiu L, Jiang H, Zhou C, Wang J, Yu Y, Zhao H, Huang T, Gropler R, Perlmutter JS, Benzinger TLS, Tu Z. Qiu L, et al. J Med Chem. 2023 Apr 13;66(7):4671-4688. doi: 10.1021/acs.jmedchem.2c01752. Epub 2023 Mar 16. J Med Chem. 2023. PMID: 36926861 Free PMC article.

7

Characterization of a S1PR2 specific ¹¹C-labeled radiotracer in streptozotocin-induced diabetic murine model.

Jiang H, Huang T, Yu Y, Zhou C, Qiu L, Mai HN, Gropler RJ, Klein RS, Tu Z. Jiang H, et al. Among authors: qiu l. Nucl Med Biol. 2023 Jul-Aug;122-123:108370. doi: 10.1016/j.nucmedbio.2023.108370. Epub 2023 Jul 26. Nucl Med Biol. 2023. PMID: 37556928 Free PMC article.

8

Quantitative Analysis of S1PR1 Expression in the Postmortem Multiple Sclerosis Central Nervous System.

Jiang H, Zhou C, Qiu L, Gropler RJ, Brier MR, Wu GF, Cross AH, Perlmutter JS, Benzinger TLS, Tu Z. Jiang H, et al. Among authors: qiu l. ACS Chem Neurosci. 2023 Nov 15;14(22):4039-4050. doi: 10.1021/acschemneuro.3c00581. Epub 2023 Oct 26. ACS Chem Neurosci. 2023. PMID: 37882753 Free PMC article.

9

Development of a CCR2 targeted ¹⁸F-labeled radiotracer for atherosclerosis imaging with PET.

Zhang X, Qiu L, Sultan DH, Luehmann HP, Yu Y, Zhang X, Heo GS, Li A, Lahad D, Rho S, Tu Z, Liu Y. Zhang X, et al. Among authors: qiu l. Nucl Med Biol. 2024 Mar-Apr;130-131:108893. doi: 10.1016/j.nucmedbio.2024.108893. Epub 2024 Feb 23. Nucl Med Biol. 2024. PMID: 38422918

10

PET Imaging of Sphingosine-1-Phosphate Receptor 1 with [18F]TZ4877 in Nonhuman Primates.

Gu J, Zheng MQ, Holden D, Fowles K, Qiu L, Felchner Z, Zhang L, Ropchan J, Gropler RJ, Carson RE, Tu Z, Huang Y, Hillmer AT. Gu J, et al. Among authors: qiu l. Res Sq [Preprint]. 2024 May 30:rs.3.rs-4350862. doi: 10.21203/rs.3.rs-4350862/v1. Res Sq. 2024. PMID: 38854065 Free PMC article. Preprint.

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