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Novel sulfamethoxazole and 1-(2-fluorophenyl) piperazine derivatives as potential apoptotic and antiproliferative agents by inhibition of BCL2; design, synthesis, biological evaluation, and docking studies.
Vadabingi N, Mallepogu V, Mallapu RE, Pasala C, Poreddy S, Bellala P, Amineni U, Cirandur SR, Meriga B. Vadabingi N, et al. Among authors: pasala c. 3 Biotech. 2024 Nov;14(11):269. doi: 10.1007/s13205-024-04111-6. Epub 2024 Oct 15. 3 Biotech. 2024. PMID: 39421851
Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation.
Roychowdhury T, McNutt SW, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, De Stanchina E, Corben A, Modi S, Alpaugh ML, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. Roychowdhury T, et al. Among authors: pasala c. Nat Commun. 2024 Oct 16;15(1):8912. doi: 10.1038/s41467-024-53178-5. Nat Commun. 2024. PMID: 39414766 Free PMC article.
Cracking the chaperone code through the computational microscope.
Guarra F, Sciva C, Bonollo G, Pasala C, Chiosis G, Moroni E, Colombo G. Guarra F, et al. Among authors: pasala c. Cell Stress Chaperones. 2024 Oct;29(5):626-640. doi: 10.1016/j.cstres.2024.08.001. Epub 2024 Aug 12. Cell Stress Chaperones. 2024. PMID: 39142378 Free PMC article. Review.
Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders.
Bay S, Digwal CS, Rodilla Martín AM, Sharma S, Stanisavljevic A, Rodina A, Attaran A, Roychowdhury T, Parikh K, Toth E, Panchal P, Rosiek E, Pasala C, Arancio O, Fraser PE, Alldred MJ, Prado MAM, Ginsberg SD, Chiosis G. Bay S, et al. Among authors: pasala c. Biomedicines. 2024 Jun 4;12(6):1252. doi: 10.3390/biomedicines12061252. Biomedicines. 2024. PMID: 38927459 Free PMC article.
Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation.
McNutt SW, Roychowdhury T, Pasala C, Nguyen HT, Thornton DT, Sharma S, Botticelli L, Digwal CS, Joshi S, Yang N, Panchal P, Chakrabarty S, Bay S, Markov V, Kwong C, Lisanti J, Chung SY, Ginsberg SD, Yan P, DeStanchina E, Corben A, Modi S, Alpaugh M, Colombo G, Erdjument-Bromage H, Neubert TA, Chalkley RJ, Baker PR, Burlingame AL, Rodina A, Chiosis G, Chu F. McNutt SW, et al. Among authors: pasala c. Res Sq [Preprint]. 2024 Apr 3:rs.3.rs-4114038. doi: 10.21203/rs.3.rs-4114038/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Oct 16;15(1):8912. doi: 10.1038/s41467-024-53178-5 PMID: 38645031 Free PMC article. Updated. Preprint.
Design, synthesis, anti-tobacco mosaic viral and molecule docking simulations of urea/thiourea derivatives of 2-(piperazine-1-yl)-pyrimidine and 1-(4-Fluoro/4-Chloro phenyl)-piperazine and 1-(4-Chloro phenyl)-piperazine - A study.
Nagalakshmamma V, Venkataswamy M, Pasala C, Umamaheswari A, Thyagaraju K, Nagaraju C, Chalapathi PV. Nagalakshmamma V, et al. Among authors: pasala c. Bioorg Chem. 2020 Sep;102:104084. doi: 10.1016/j.bioorg.2020.104084. Epub 2020 Jul 10. Bioorg Chem. 2020. PMID: 32693309
17 results