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Page 1
Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: garibotti mc. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588639. doi: 10.1101/2024.04.08.588639. bioRxiv. 2024. Update in: Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. PMID: 38645227 Free PMC article. Updated. Preprint.
Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress.
Delfinis LJ, Bellissimo CA, Gandhi S, DiBenedetto SN, Garibotti MC, Thuhan AK, Tsitkanou S, Rosa-Caldwell ME, Rahman FA, Cheng AJ, Wiggs MP, Schlattner U, Quadrilatero J, Greene NP, Perry CG. Delfinis LJ, et al. Among authors: garibotti mc. JCI Insight. 2022 Dec 22;7(24):e155147. doi: 10.1172/jci.insight.155147. JCI Insight. 2022. PMID: 36346680 Free PMC article.
Strength athletes and mitochondria: it's about 'time'.
Garibotti MC, Perry CGR. Garibotti MC, et al. J Physiol. 2023 Jul;601(14):2753-2754. doi: 10.1113/JP284856. Epub 2023 Jun 22. J Physiol. 2023. PMID: 37306149 Free article. No abstract available.
The slow-release adiponectin analog ALY688-SR modifies early-stage disease development in the D2.mdx mouse model of Duchenne muscular dystrophy.
Bellissimo CA, Gandhi S, Castellani LN, Murugathasan M, Delfinis LJ, Thuhan A, Garibotti MC, Seo Y, Rebalka IA, Hsu HH, Sweeney G, Hawke TJ, Abdul-Sater AA, Perry CGR. Bellissimo CA, et al. Among authors: garibotti mc. Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1011-C1026. doi: 10.1152/ajpcell.00638.2023. Epub 2023 Dec 25. Am J Physiol Cell Physiol. 2024. PMID: 38145301
Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: garibotti mc. Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. Epub 2024 Jun 24. Mol Metab. 2024. PMID: 38925248 Free PMC article.
Cardiac Atrophy, Dysfunction, and Metabolic Impairments: A Cancer-Induced Cardiomyopathy Phenotype.
Ogilvie LM, Delfinis LJ, Coyle-Asbil B, Vudatha V, Alshamali R, Garlisi B, Pereira M, Matuszewska K, Garibotti MC, Gandhi S, Brunt KR, Wood GA, Trevino JG, Perry CGR, Petrik J, Simpson JA. Ogilvie LM, et al. Among authors: garibotti mc. Am J Pathol. 2024 Oct;194(10):1823-1843. doi: 10.1016/j.ajpath.2024.06.008. Epub 2024 Jul 18. Am J Pathol. 2024. PMID: 39032600 Free article.
Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20.
Hughes MC, Ramos SV, Brahmbhatt AN, Turnbull PC, Polidovitch NN, Garibotti MC, Schlattner U, Hawke TJ, Simpson JA, Backx PH, Perry CG. Hughes MC, et al. Among authors: garibotti mc. Redox Biol. 2024 Oct;76:103319. doi: 10.1016/j.redox.2024.103319. Epub 2024 Aug 20. Redox Biol. 2024. PMID: 39178732 Free PMC article.
Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice.
Delfinis LJ, Khajehzadehshoushtar S, Flewwelling LD, Andrews NJ, Garibotti MC, Gandhi S, Brahmbhatt AN, Morris BA, Garlisi B, Lauks S, Aitken C, Tsitkanou S, Simpson JA, Greene NP, Cheng AJ, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: garibotti mc. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.619751. doi: 10.1101/2024.10.22.619751. bioRxiv. 2024. PMID: 39484418 Free PMC article. Preprint.