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Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: greene np. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588639. doi: 10.1101/2024.04.08.588639. bioRxiv. 2024. Update in: Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. PMID: 38645227 Free PMC article. Updated. Preprint.
Exercise Counteracts the Deleterious Effects of Cancer Cachexia.
Tsitkanou S, Murach KA, Washington TA, Greene NP. Tsitkanou S, et al. Among authors: greene np. Cancers (Basel). 2022 May 19;14(10):2512. doi: 10.3390/cancers14102512. Cancers (Basel). 2022. PMID: 35626116 Free PMC article. Review.
Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress.
Delfinis LJ, Bellissimo CA, Gandhi S, DiBenedetto SN, Garibotti MC, Thuhan AK, Tsitkanou S, Rosa-Caldwell ME, Rahman FA, Cheng AJ, Wiggs MP, Schlattner U, Quadrilatero J, Greene NP, Perry CG. Delfinis LJ, et al. Among authors: greene np. JCI Insight. 2022 Dec 22;7(24):e155147. doi: 10.1172/jci.insight.155147. JCI Insight. 2022. PMID: 36346680 Free PMC article.
A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle.
Jones RG 3rd, Dimet-Wiley A, Haghani A, da Silva FM, Brightwell CR, Lim S, Khadgi S, Wen Y, Dungan CM, Brooke RT, Greene NP, Peterson CA, McCarthy JJ, Horvath S, Watowich SJ, Fry CS, Murach KA. Jones RG 3rd, et al. Among authors: greene np. J Physiol. 2023 Feb;601(4):763-782. doi: 10.1113/JP283836. Epub 2023 Jan 24. J Physiol. 2023. PMID: 36533424 Free PMC article.
Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: greene np. Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. Epub 2024 Jun 24. Mol Metab. 2024. PMID: 38925248 Free PMC article.
Mitochondrial antioxidant SkQ1 attenuates C26 cancer-induced muscle wasting in males and improves muscle contractility in female tumor-bearing mice.
Tsitkanou S, Morena da Silva F, Cabrera AR, Schrems ER, Muhyudin R, Koopmans PJ, Khadgi S, Lim S, Delfinis LJ, Washington TA, Murach KA, Perry CGR, Greene NP. Tsitkanou S, et al. Among authors: greene np. Am J Physiol Cell Physiol. 2024 Nov 1;327(5):C1308-C1322. doi: 10.1152/ajpcell.00497.2024. Epub 2024 Sep 30. Am J Physiol Cell Physiol. 2024. PMID: 39344417
90 results