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Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: simpson ja. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588639. doi: 10.1101/2024.04.08.588639. bioRxiv. 2024. Update in: Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. PMID: 38645227 Free PMC article. Updated. Preprint.
Muscle weakness and mitochondrial stress occur before severe metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: simpson ja. Mol Metab. 2024 Aug;86:101976. doi: 10.1016/j.molmet.2024.101976. Epub 2024 Jun 24. Mol Metab. 2024. PMID: 38925248 Free PMC article.
Mitohormesis during advanced stages of Duchenne muscular dystrophy reveals a redox-sensitive creatine pathway that can be enhanced by the mitochondrial-targeting peptide SBT-20.
Hughes MC, Ramos SV, Brahmbhatt AN, Turnbull PC, Polidovitch NN, Garibotti MC, Schlattner U, Hawke TJ, Simpson JA, Backx PH, Perry CG. Hughes MC, et al. Among authors: simpson ja. Redox Biol. 2024 Oct;76:103319. doi: 10.1016/j.redox.2024.103319. Epub 2024 Aug 20. Redox Biol. 2024. PMID: 39178732 Free PMC article.
Mitochondrial-targeted plastoquinone therapy ameliorates early onset muscle weakness that precedes ovarian cancer cachexia in mice.
Delfinis LJ, Khajehzadehshoushtar S, Flewwelling LD, Andrews NJ, Garibotti MC, Gandhi S, Brahmbhatt AN, Morris BA, Garlisi B, Lauks S, Aitken C, Tsitkanou S, Simpson JA, Greene NP, Cheng AJ, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: simpson ja. bioRxiv [Preprint]. 2024 Oct 25:2024.10.22.619751. doi: 10.1101/2024.10.22.619751. bioRxiv. 2024. PMID: 39484418 Free PMC article. Preprint.
Reduced red blood cell deformability in vivax malaria.
Rathnam JTT, Grigg MJ, Dondorp AM, William T, Rajasekhar M, Rajahram G, Simpson JA, Barber BE, Anstey NM. Rathnam JTT, et al. Among authors: simpson ja. J Infect Dis. 2024 Oct 7:jiae490. doi: 10.1093/infdis/jiae490. Online ahead of print. J Infect Dis. 2024. PMID: 39374370
Primaquine for uncomplicated Plasmodium vivax malaria in children younger than 15 years: a systematic review and individual patient data meta-analysis.
Commons RJ, Rajasekhar M, Allen EN, Yilma D, Chotsiri P, Abreha T, Adam I, Awab GR, Barber BE, Brasil LW, Chu CS, Cui L, Edler P, Gomes MDSM, Gonzalez-Ceron L, Grigg MJ, Hamid MMA, Hwang J, Karunajeewa H, Lacerda MVG, Ladeia-Andrade S, Leslie T, Longley RJ, Monteiro WM, Pasaribu AP, Poespoprodjo JR, Richmond CL, Rijal KR, Taylor WRJ, Thanh PV, Thriemer K, Vieira JLF, White NJ, Zuluaga-Idarraga LM, Workman LJ, Tarning J, Stepniewska K, Guerin PJ, Simpson JA, Barnes KI, Price RN; WorldWide Antimalarial Resistance Network Paediatric Primaquine Vivax Study Group. Commons RJ, et al. Among authors: simpson ja. Lancet Child Adolesc Health. 2024 Nov;8(11):798-808. doi: 10.1016/S2352-4642(24)00210-4. Epub 2024 Sep 24. Lancet Child Adolesc Health. 2024. PMID: 39332427 Free PMC article.
A systems serology approach to identifying key antibody correlates of protection from cerebral malaria in Malawian children.
Walker IS, Dini S, Aitken EH, Damelang T, Hasang W, Alemu A, Jensen ATR, Rambhatla JS, Opi DH, Duffy MF, Takashima E, Harawa V, Tsuboi T, Simpson JA, Mandala W, Taylor TE, Seydel KB, Chung AW, Rogerson SJ. Walker IS, et al. Among authors: simpson ja. BMC Med. 2024 Sep 12;22(1):388. doi: 10.1186/s12916-024-03604-8. BMC Med. 2024. PMID: 39267089 Free PMC article.
760 results