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Page 1
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST.
Sprenger HG, Mittenbühler MJ, Sun Y, Van Vranken JG, Schindler S, Jayaraj A, Khetarpal SA, Vargas-Castillo A, Puszynska AM, Spinelli JB, Armani A, Kunchok T, Ryback B, Seo HS, Song K, Sebastian L, O'Young C, Braithwaite C, Dhe-Paganon S, Burger N, Mills EL, Gygi SP, Arthanari H, Chouchani ET, Sabatini DM, Spiegelman BM. Sprenger HG, et al. Among authors: spiegelman bm. bioRxiv [Preprint]. 2024 Apr 10:2024.04.10.588849. doi: 10.1101/2024.04.10.588849. bioRxiv. 2024. PMID: 38645260 Free PMC article. Preprint.
Mustn1 is a smooth muscle cell-secreted microprotein that modulates skeletal muscle extracellular matrix composition.
Ducommun S, Jannig PR, Cervenka I, Murgia M, Mittenbühler MJ, Chernogubova E, Dias JM, Jude B, Correia JC, Van Vranken JG, Ocana-Santero G, Porsmyr-Palmertz M, McCann Haworth S, Martínez-Redondo V, Liu Z, Carlström M, Mann M, Lanner JT, Teixeira AI, Maegdefessel L, Spiegelman BM, Ruas JL. Ducommun S, et al. Among authors: spiegelman bm. Mol Metab. 2024 Apr;82:101912. doi: 10.1016/j.molmet.2024.101912. Epub 2024 Mar 6. Mol Metab. 2024. PMID: 38458566 Free PMC article.
Development of a functional beige fat cell line uncovers independent subclasses of cells expressing UCP1 and the futile creatine cycle.
Vargas-Castillo A, Sun Y, Smythers AL, Grauvogel L, Dumesic PA, Emont MP, Tsai LT, Rosen ED, Zammit NW, Shaffer SM, Ordonez M, Chouchani ET, Gygi SP, Wang T, Sharma AK, Balaz M, Wolfrum C, Spiegelman BM. Vargas-Castillo A, et al. Among authors: spiegelman bm. Cell Metab. 2024 Sep 3;36(9):2146-2155.e5. doi: 10.1016/j.cmet.2024.07.002. Epub 2024 Jul 30. Cell Metab. 2024. PMID: 39084217
Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes.
Wang T, Sharma AK, Wu C, Maushart CI, Ghosh A, Yang W, Stefanicka P, Kovanicova Z, Ukropec J, Zhang J, Arnold M, Klug M, De Bock K, Schneider U, Popescu C, Zheng B, Ding L, Long F, Dewal RS, Moser C, Sun W, Dong H, Takes M, Suelberg D, Mameghani A, Nocito A, Zech CJ, Chirindel A, Wild D, Burger IA, Schön MR, Dietrich A, Gao M, Heine M, Sun Y, Vargas-Castillo A, Søberg S, Scheele C, Balaz M, Blüher M, Betz MJ, Spiegelman BM, Wolfrum C. Wang T, et al. Among authors: spiegelman bm. Cell Metab. 2024 Sep 3;36(9):2130-2145.e7. doi: 10.1016/j.cmet.2024.07.005. Epub 2024 Jul 30. Cell Metab. 2024. PMID: 39084216 Free article.
p38α kinase governs muscle strength through PGC1α in mice.
Herrera-Melle L, Cicuéndez B, López JA, Dumesic PA, Wilensky SE, Rodríguez E, Leiva-Vega L, Caballero A, León M, Vázquez J, Spiegelman BM, Folgueira C, Mora A, Sabio G. Herrera-Melle L, et al. Among authors: spiegelman bm. Acta Physiol (Oxf). 2024 Nov;240(11):e14234. doi: 10.1111/apha.14234. Epub 2024 Oct 3. Acta Physiol (Oxf). 2024. PMID: 39361268
Remodeling p38 signaling in muscle controls locomotor activity via IL-15.
Folgueira C, Herrera-Melle L, López JA, Galvan-Alvarez V, Martin-Rincon M, Cuartero MI, García-Culebras A, Dumesic PA, Rodríguez E, Leiva-Vega L, León M, Porteiro B, Iglesias C, Torres JL, Hernández-Cosido L, Bonacasa C, Marcos M, Moro MÁ, Vázquez J, Calbet JAL, Spiegelman BM, Mora A, Sabio G. Folgueira C, et al. Among authors: spiegelman bm. Sci Adv. 2024 Aug 16;10(33):eadn5993. doi: 10.1126/sciadv.adn5993. Epub 2024 Aug 14. Sci Adv. 2024. PMID: 39141732 Free PMC article.
359 results