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Page 1
Remethylation of Dnmt3a-/- hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing.
Ketkar S, Verdoni AM, Smith AM, Bangert CV, Leight ER, Chen DY, Brune MK, Helton NM, Hoock M, George DR, Fronick C, Fulton RS, Ramakrishnan SM, Chang GS, Petti AA, Spencer DH, Miller CA, Ley TJ. Ketkar S, et al. Among authors: ley tj. Proc Natl Acad Sci U S A. 2020 Feb 11;117(6):3123-3134. doi: 10.1073/pnas.1918611117. Epub 2020 Jan 29. Proc Natl Acad Sci U S A. 2020. PMID: 31996479 Free PMC article.
Tumor suppressor function of Gata2 in acute promyelocytic leukemia.
Katerndahl CDS, Rogers ORS, Day RB, Cai MA, Rooney TP, Helton NM, Hoock M, Ramakrishnan SM, Nonavinkere Srivatsan S, Wartman LD, Miller CA, Ley TJ. Katerndahl CDS, et al. Among authors: ley tj. Blood. 2021 Sep 30;138(13):1148-1161. doi: 10.1182/blood.2021011758. Blood. 2021. PMID: 34125173 Free PMC article.
Immunosuppression and outcomes in adult patients with de novo acute myeloid leukemia with normal karyotypes.
Ferraro F, Miller CA, Christensen KA, Helton NM, O'Laughlin M, Fronick CC, Fulton RS, Kohlschmidt J, Eisfeld AK, Bloomfield CD, Ramakrishnan SM, Day RB, Wartman LD, Uy GL, Welch JS, Christopher MJ, Heath SE, Baty JD, Schuelke MJ, Payton JE, Spencer DH, Rettig MP, Link DC, Walter MJ, Westervelt P, DiPersio JF, Ley TJ. Ferraro F, et al. Among authors: ley tj. Proc Natl Acad Sci U S A. 2021 Dec 7;118(49):e2116427118. doi: 10.1073/pnas.2116427118. Proc Natl Acad Sci U S A. 2021. PMID: 34845035 Free PMC article.
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia.
Kramer MH, Zhang Q, Sprung R, Day RB, Erdmann-Gilmore P, Li Y, Xu Z, Helton NM, George DR, Mi Y, Westervelt P, Payton JE, Ramakrishnan SM, Miller CA, Link DC, DiPersio JF, Walter MJ, Townsend RR, Ley TJ. Kramer MH, et al. Among authors: ley tj. Blood. 2022 Sep 29;140(13):1533-1548. doi: 10.1182/blood.2022016033. Blood. 2022. PMID: 35895896 Free PMC article.
Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells.
Spencer DH, Young MA, Lamprecht TL, Helton NM, Fulton R, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Miller CA, Klco JM, Wilson RK, Ley TJ. Spencer DH, et al. Among authors: ley tj. Leukemia. 2015 Jun;29(6):1279-89. doi: 10.1038/leu.2015.6. Epub 2015 Jan 20. Leukemia. 2015. PMID: 25600023 Free PMC article.
Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies.
Cole CB, Russler-Germain DA, Ketkar S, Verdoni AM, Smith AM, Bangert CV, Helton NM, Guo M, Klco JM, O'Laughlin S, Fronick C, Fulton R, Chang GS, Petti AA, Miller CA, Ley TJ. Cole CB, et al. Among authors: ley tj. J Clin Invest. 2017 Oct 2;127(10):3657-3674. doi: 10.1172/JCI93041. Epub 2017 Sep 5. J Clin Invest. 2017. PMID: 28872462 Free PMC article.
265 results