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Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer.
Pfeifer M, Brammeld JS, Price S, Pilling J, Bhavsar D, Farcas A, Bateson J, Sundarrajan A, Miragaia RJ, Guan N, Arnold S, Tariq L, Grondine M, Talbot S, Guerriero ML, O'Neill DJ, Young J, Company C, Dunn S, Thorpe H, Martin MJ, Maratea K, Barrell D, Ahdesmaki M, Mettetal JT; Functional Genomics Centre; Brownell J, McDermott U. Pfeifer M, et al. Commun Biol. 2024 Apr 24;7(1):497. doi: 10.1038/s42003-024-06190-w. Commun Biol. 2024. PMID: 38658677 Free PMC article.
Knowledge graph-based recommendation framework identifies drivers of resistance in EGFR mutant non-small cell lung cancer.
Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin MJ, Thorpe H, Bornot A, Smith PD, Sidders B, Dry JR, Ahdesmäki M, McDermott U, Papa E, Bulusu KC. Gogleva A, et al. Among authors: pfeifer m. Nat Commun. 2022 Mar 29;13(1):1667. doi: 10.1038/s41467-022-29292-7. Nat Commun. 2022. PMID: 35351890 Free PMC article.
A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components.
Nilsson MB, Sun H, Robichaux J, Pfeifer M, McDermott U, Travers J, Diao L, Xi Y, Tong P, Shen L, Hofstad M, Kawakami M, Le X, Liu X, Fan Y, Poteete A, Hu L, Negrao MV, Tran H, Dmitrovsky E, Peng D, Gibbons DL, Wang J, Heymach JV. Nilsson MB, et al. Among authors: pfeifer m. Sci Transl Med. 2020 Sep 2;12(559):eaaz4589. doi: 10.1126/scitranslmed.aaz4589. Sci Transl Med. 2020. PMID: 32878980 Free PMC article.
Overcoming Osimertinib Resistance with AKT Inhibition in EGFRm-Driven Non-Small Cell Lung Cancer with PIK3CA/PTEN Alterations.
Grazini U, Markovets A, Ireland L, O'Neill D, Phillips B, Xu M, Pfeifer M, Vaclova T, Martin MJ, Bigot L, Friboulet L, Hartmaier R, Cuomo ME, Barry ST, Smith PD, Floc'h N. Grazini U, et al. Among authors: pfeifer m. Clin Cancer Res. 2024 Sep 13;30(18):4143-4154. doi: 10.1158/1078-0432.CCR-23-2540. Clin Cancer Res. 2024. PMID: 38630555
Effects of Climate, Soil, Topography and Disturbance on Liana Prevalence.
Mackintosh EJ, Waite CE, Putz FE, Pfeifer M, Chen C, Lan Z, Brennan S, Marshall AR. Mackintosh EJ, et al. Among authors: pfeifer m. Ecol Evol. 2024 Oct 10;14(10):e70374. doi: 10.1002/ece3.70374. eCollection 2024 Oct. Ecol Evol. 2024. PMID: 39391818 Free PMC article.
789 results