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Utilizing PK and PD Biomarkers to Guide the First-in-Human Starting Dose Selection of MTBT1466A: A Novel Humanized Monoclonal Anti-TGFβ3 Antibody for the Treatment of Fibrotic Diseases.
Yadav R, Sukumaran S, Lutman J, Mitra MS, Halpern W, Sun T, Setiadi AF, Neighbors M, Sheng XR, Yip V, Shen BQ, Liu C, Han L, Ovacik AM, Wu Y, Glickstein S, Kunder R, Arron JR, Pan L, Kamath AV, Stefanich EG. Yadav R, et al. J Pharm Sci. 2023 Nov;112(11):2910-2920. doi: 10.1016/j.xphs.2023.07.005. Epub 2023 Jul 8. J Pharm Sci. 2023. PMID: 37429356 Free article.
Safety and efficacy of zinpentraxin alfa as monotherapy or in combination with ruxolitinib in myelofibrosis: stage I of a phase II trial.
Verstovsek S, Foltz L, Gupta V, Hasserjian R, Manshouri T, Mascarenhas J, Mesa R, Pozdnyakova O, Ritchie E, Veletic I, Gamel K, Hamidi H, Han L, Higgins B, Trunzer K, Uguen M, Wang D, El-Galaly TC, Todorov B, Gotlib J. Verstovsek S, et al. Haematologica. 2023 Oct 1;108(10):2730-2742. doi: 10.3324/haematol.2022.282411. Haematologica. 2023. PMID: 37165840 Free PMC article. Clinical Trial.
Efflux transporters in drug disposition during pregnancy.
Chen X, Gao C, Han LW, Heidelberger S, Liao MZ, Neradugomma NK, Ni Z, Shuster DL, Wang H, Zhang Y, Zhou L. Chen X, et al. Among authors: han lw. Drug Metab Dispos. 2024 May 29:DMD-MR-2023-001385. doi: 10.1124/dmd.123.001385. Online ahead of print. Drug Metab Dispos. 2024. PMID: 38811158 Free article.
57 results