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The CXCL1 rs4074 A allele is associated with enhanced CXCL1 responses to TLR2 ligands and predisposes to cirrhosis in HCV genotype 1-infected Caucasian patients.
Nischalke HD, Berger C, Luda C, Müller T, Berg T, Coenen M, Krämer B, Körner C, Trebicka J, Grünhage F, Lammert F, Nattermann J, Sauerbruch T, Spengler U. Nischalke HD, et al. J Hepatol. 2012 Apr;56(4):758-64. doi: 10.1016/j.jhep.2011.10.019. Epub 2011 Dec 13. J Hepatol. 2012. PMID: 22173151
Hypoxia impairs anti-viral activity of natural killer (NK) cells but has little effect on anti-fibrotic NK cell functions in hepatitis C virus infection.
Wolter F, Glässner A, Krämer B, Kokordelis P, Finnemann C, Kaczmarek DJ, Goeser F, Lutz P, Nischalke HD, Strassburg CP, Spengler U, Nattermann J. Wolter F, et al. Among authors: nischalke hd. J Hepatol. 2015 Dec;63(6):1334-44. doi: 10.1016/j.jhep.2015.08.008. Epub 2015 Aug 20. J Hepatol. 2015. PMID: 26297916
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