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In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.
Turoňová B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, von Bülow S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Landry J, de Azevedo NTD, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M. Turoňová B, et al. Among authors: beck m. Science. 2020 Oct 9;370(6513):203-208. doi: 10.1126/science.abd5223. Epub 2020 Aug 18. Science. 2020. PMID: 32817270 Free PMC article.
In-cell architecture of the nuclear pore and snapshots of its turnover.
Allegretti M, Zimmerli CE, Rantos V, Wilfling F, Ronchi P, Fung HKH, Lee CW, Hagen W, Turoňová B, Karius K, Börmel M, Zhang X, Müller CW, Schwab Y, Mahamid J, Pfander B, Kosinski J, Beck M. Allegretti M, et al. Among authors: beck m. Nature. 2020 Oct;586(7831):796-800. doi: 10.1038/s41586-020-2670-5. Epub 2020 Sep 2. Nature. 2020. PMID: 32879490
Structural biology in the fight against COVID-19.
Bárcena M, Barnes CO, Beck M, Bjorkman PJ, Canard B, Gao GF, Gao Y, Hilgenfeld R, Hummer G, Patwardhan A, Santoni G, Saphire EO, Schaffitzel C, Schendel SL, Smith JL, Thorn A, Veesler D, Zhang P, Zhou Q. Bárcena M, et al. Among authors: beck m. Nat Struct Mol Biol. 2021 Jan;28(1):2-7. doi: 10.1038/s41594-020-00544-8. Nat Struct Mol Biol. 2021. PMID: 33437043 No abstract available.
Cone-shaped HIV-1 capsids are transported through intact nuclear pores.
Zila V, Margiotta E, Turoňová B, Müller TG, Zimmerli CE, Mattei S, Allegretti M, Börner K, Rada J, Müller B, Lusic M, Kräusslich HG, Beck M. Zila V, et al. Among authors: beck m. Cell. 2021 Feb 18;184(4):1032-1046.e18. doi: 10.1016/j.cell.2021.01.025. Epub 2021 Feb 10. Cell. 2021. PMID: 33571428 Free PMC article.
Nuclear pores dilate and constrict in cellulo.
Zimmerli CE, Allegretti M, Rantos V, Goetz SK, Obarska-Kosinska A, Zagoriy I, Halavatyi A, Hummer G, Mahamid J, Kosinski J, Beck M. Zimmerli CE, et al. Among authors: beck m. Science. 2021 Dec 10;374(6573):eabd9776. doi: 10.1126/science.abd9776. Epub 2021 Dec 10. Science. 2021. PMID: 34762489 Free article.
A modular platform for automated cryo-FIB workflows.
Klumpe S, Fung HK, Goetz SK, Zagoriy I, Hampoelz B, Zhang X, Erdmann PS, Baumbach J, Müller CW, Beck M, Plitzko JM, Mahamid J. Klumpe S, et al. Among authors: beck m. Elife. 2021 Dec 24;10:e70506. doi: 10.7554/eLife.70506. Elife. 2021. PMID: 34951584 Free PMC article.
Co-translational assembly orchestrates competing biogenesis pathways.
Seidel M, Becker A, Pereira F, Landry JJM, de Azevedo NTD, Fusco CM, Kaindl E, Romanov N, Baumbach J, Langer JD, Schuman EM, Patil KR, Hummer G, Benes V, Beck M. Seidel M, et al. Among authors: beck m. Nat Commun. 2022 Mar 9;13(1):1224. doi: 10.1038/s41467-022-28878-5. Nat Commun. 2022. PMID: 35264577 Free PMC article.
2,443 results