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Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma.
Mizuguchi M, Nakagawa Y, Yokoyama T, Okada T, Fujii K, Takahashi K, Luan NNT, Nabeshima Y, Kanamitsu K, Nakagawa S, Yamakawa S, Ueda M, Ando Y, Toyooka N. Mizuguchi M, et al. Among authors: nakagawa s, nakagawa y. J Med Chem. 2024 Apr 26;67(9):6987-7005. doi: 10.1021/acs.jmedchem.3c02286. Online ahead of print. J Med Chem. 2024. PMID: 38670538 Free PMC article.
Conversion of a PROTAC Mutant Huntingtin Degrader into Small-Molecule Hydrophobic Tags Focusing on Drug-like Properties.
Hirai K, Yamashita H, Tomoshige S, Mishima Y, Niwa T, Ohgane K, Ishii M, Kanamitsu K, Ikemi Y, Nakagawa S, Taguchi H, Sato S, Hashimoto Y, Ishikawa M. Hirai K, et al. Among authors: nakagawa s. ACS Med Chem Lett. 2022 Feb 16;13(3):396-402. doi: 10.1021/acsmedchemlett.1c00500. eCollection 2022 Mar 10. ACS Med Chem Lett. 2022. PMID: 35300080 Free PMC article.
Chlorinated Naringenin Analogues as Potential Inhibitors of Transthyretin Amyloidogenesis.
Mizuguchi M, Nakagawa Y, Inui K, Katayama W, Sawai Y, Shimane A, Kitakami R, Okada T, Nabeshima Y, Yokoyama T, Kanamitsu K, Nakagawa S, Toyooka N. Mizuguchi M, et al. Among authors: nakagawa s, nakagawa y. J Med Chem. 2022 Dec 22;65(24):16218-16233. doi: 10.1021/acs.jmedchem.2c00511. Epub 2022 Dec 6. J Med Chem. 2022. PMID: 36472374
[Creation of TNFR1-selective antagonist and its therapeutic effects].
Nomura T, Abe Y, Yoshioka Y, Nakagawa S, Tsunoda S, Tsutsumi Y. Nomura T, et al. Among authors: nakagawa s. Yakugaku Zasshi. 2010 Jan;130(1):63-8. doi: 10.1248/yakushi.130.63. Yakugaku Zasshi. 2010. PMID: 20046067 Free article. Review. Japanese.
3,861 results