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Triple knockdown of CD11a, CD49d, and PSGL1 in T cells reduces CAR-T cell toxicity but preserves activity against solid tumors in mice.
Wang H, Wu Z, Cui D, Bian L, Zheng Z, Zhu J, Geng H, Sun Z, Pan Y, Shi Y, Yi Q, Song Z, Li Y, Shen K, Li Y, Shen W, Yan H, Hao R, Sun M, Zhang S, Zhang C, Jin H, Zhai B. Wang H, et al. Among authors: shi y. Sci Transl Med. 2025 Jan 22;17(782):eadl6432. doi: 10.1126/scitranslmed.adl6432. Epub 2025 Jan 22. Sci Transl Med. 2025. PMID: 39841806
CAMKIIδ Reinforces Lipid Metabolism and Promotes the Development of B Cell Lymphoma.
Zhang J, Xu S, Fang H, Wu D, Ouyang C, Shi Y, Hu Z, Zhang M, Zhong Y, Zhao J, Gan Y, Zhang S, Liu X, Yin J, Li Y, Tang M, Wang Y, Li L, Chan WC, Horne D, Feng M, Huang W, Gu Y. Zhang J, et al. Among authors: shi y. Adv Sci (Weinh). 2025 Jan 22:e2409513. doi: 10.1002/advs.202409513. Online ahead of print. Adv Sci (Weinh). 2025. PMID: 39840457
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