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Dietary dicarboxylic acids provide a non-storable alternative fat source that protects mice against obesity.
Goetzman ES, Zhang BB, Zhang Y, Bharathi SS, Bons J, Rose J, Shah S, Solo KJ, Schmidt AV, Richert AC, Mullett SJ, Gelhaus SL, Rao KS, Shiva SS, Pfister KE, Silva Barbosa A, Sims-Lucas S, Dobrowolski SF, Schilling B. Goetzman ES, et al. Among authors: mullett sj. J Clin Invest. 2024 Apr 30;134(12):e174186. doi: 10.1172/JCI174186. Online ahead of print. J Clin Invest. 2024. PMID: 38687608 Free PMC article.
Vitamin C Is Mandatory for the Tricarboxylic Acid Cycle Production of Antiinflammatory Itaconate.
Soysal E, Castellano E, Korkmaz A, Mullett SJ, Kim-Campbell N, Epperly M, Wendell S, Kagan VE, Bayır H; Redox Health Study Group. Soysal E, et al. Among authors: mullett sj. Am J Respir Crit Care Med. 2023 Dec 1;208(11):1234-1238. doi: 10.1164/rccm.202304-0636LE. Am J Respir Crit Care Med. 2023. PMID: 37782815 Free PMC article. No abstract available.
Drp1 splice variants regulate ovarian cancer mitochondrial dynamics and tumor progression.
Javed Z, Shin DH, Pan W, White SR, Elhaw AT, Kim YS, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: mullett sj. EMBO Rep. 2024 Oct;25(10):4281-4310. doi: 10.1038/s44319-024-00232-4. Epub 2024 Aug 27. EMBO Rep. 2024. PMID: 39191946 Free PMC article.
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling.
Koudelka A, Buchan GJ, Cechova V, O'Brien JP, Liu H, Woodcock SR, Mullett SJ, Zhang C, Freeman BA, Gelhaus SL. Koudelka A, et al. Among authors: mullett sj. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.579101. doi: 10.1101/2024.02.06.579101. bioRxiv. 2024. Update in: J Lipid Res. 2024 Nov 19;66(1):100705. doi: 10.1016/j.jlr.2024.100705 PMID: 38370667 Free PMC article. Updated. Preprint.
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma.
Casillo SM, Gatesman TA, Chilukuri A, Varadharajan S, Johnson BJ, David Premkumar DR, Jane EP, Plute TJ, Koncar RF, Stanton AJ, Biagi-Junior CAO, Barber CS, Halbert ME, Golbourn BJ, Halligan K, Cruz AF, Mansi NM, Cheney A, Mullett SJ, Land CV, Perez JL, Myers MI, Agrawal N, Michel JJ, Chang YF, Vaske OM, MichaelRaj A, Lieberman FS, Felker J, Shiva S, Bertrand KC, Amankulor N, Hadjipanayis CG, Abdullah KG, Zinn PO, Friedlander RM, Abel TJ, Nazarian J, Venneti S, Filbin MG, Gelhaus SL, Mack SC, Pollack IF, Agnihotri S. Casillo SM, et al. Among authors: mullett sj. Cell Rep. 2024 Jan 23;43(1):113557. doi: 10.1016/j.celrep.2023.113557. Epub 2023 Dec 18. Cell Rep. 2024. PMID: 38113141 Free article.
Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and tumor progression in ovarian cancer.
Javed Z, Shin DH, Pan W, White SR, Kim YS, Elhaw AT, Kamlapurkar S, Cheng YY, Benson JC, Abdelnaby AE, Phaëton R, Wang HG, Yang S, Sullivan MLG, St Croix CM, Watkins SC, Mullett SJ, Gelhaus SL, Lee N, Coffman LG, Aird KM, Trebak M, Mythreye K, Walter V, Hempel N. Javed Z, et al. Among authors: mullett sj. bioRxiv [Preprint]. 2024 Jan 24:2023.09.20.558501. doi: 10.1101/2023.09.20.558501. bioRxiv. 2024. Update in: EMBO Rep. 2024 Oct;25(10):4281-4310. doi: 10.1038/s44319-024-00232-4 PMID: 37790404 Free PMC article. Updated. Preprint.
The gut protist Tritrichomonas arnold restrains virus-mediated loss of oral tolerance by modulating dietary antigen-presenting dendritic cells.
Medina Sanchez L, Siller M, Zeng Y, Brigleb PH, Sangani KA, Soto AS, Engl C, Laughlin CR, Rana M, Van Der Kraak L, Pandey SP, Bender MJ, Fitzgerald B, Hedden L, Fiske K, Taylor GM, Wright AP, Mehta ID, Rahman SA, Galipeau HJ, Mullett SJ, Gelhaus SL, Watkins SC, Bercik P, Nice TJ, Jabri B, Meisel M, Das J, Dermody TS, Verdú EF, Hinterleitner R. Medina Sanchez L, et al. Among authors: mullett sj. Immunity. 2023 Aug 8;56(8):1862-1875.e9. doi: 10.1016/j.immuni.2023.06.022. Epub 2023 Jul 20. Immunity. 2023. PMID: 37478853 Free PMC article.
40 results