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Page 1
Deficiency of the Deubiquitinase UCHL1 Attenuates Pulmonary Arterial Hypertension.
Tang H, Gupta A, Morrisroe SA, Bao C, Schwantes-An TH, Gupta G, Liang S, Sun Y, Chu A, Luo A, Ramamoorthi Elangovan V, Sangam S, Shi Y, Naidu SR, Jheng JR, Ciftci-Yilmaz S, Warfel NA, Hecker L, Mitra S, Coleman AW, Lutz KA, Pauciulo MW, Lai YC, Javaheri A, Dharmakumar R, Wu WH, Flaherty DP, Karnes JH, Breuils-Bonnet S, Boucherat O, Bonnet S, Yuan JX, Jacobson JR, Duarte JD, Nichols WC, Garcia JGN, Desai AA. Tang H, et al. Among authors: flaherty dp. Circulation. 2024 Jul 23;150(4):302-316. doi: 10.1161/CIRCULATIONAHA.123.065304. Epub 2024 May 2. Circulation. 2024. PMID: 38695173
Carbonic Anhydrase Inhibition as a Target for Antibiotic Synergy in Enterococci.
Chilambi GS, Wang YH, Wallace NR, Obiwuma C, Evans KM, Li Y, Shalaby MW, Flaherty DP, Shields RK, Doi Y, Van Tyne D. Chilambi GS, et al. Among authors: flaherty dp. Microbiol Spectr. 2023 Aug 17;11(4):e0396322. doi: 10.1128/spectrum.03963-22. Epub 2023 Jun 1. Microbiol Spectr. 2023. PMID: 37260400 Free PMC article.
Covalent Fragment Screening and Optimization Identifies the Chloroacetohydrazide Scaffold as Inhibitors for Ubiquitin C-terminal Hydrolase L1.
Imhoff RD, Patel R, Safdar MH, Jones HBL, Pinto-Fernandez A, Vendrell I, Chen H, Muli CS, Krabill AD, Kessler BM, Wendt MK, Das C, Flaherty DP. Imhoff RD, et al. Among authors: flaherty dp. J Med Chem. 2024 Mar 28;67(6):4496-4524. doi: 10.1021/acs.jmedchem.3c01661. Epub 2024 Mar 15. J Med Chem. 2024. PMID: 38488146
Enterococci carbonic anhydrase inhibition.
Holly KJ, Youse MS, Flaherty DP. Holly KJ, et al. Among authors: flaherty dp. Enzymes. 2024;55:283-311. doi: 10.1016/bs.enz.2024.05.011. Epub 2024 Jun 8. Enzymes. 2024. PMID: 39222994 Review.
Biochemical pharmacology of adenylyl cyclases in cancer.
Chandra Jena B, Flaherty DP, O'Brien VP, Watts VJ. Chandra Jena B, et al. Among authors: flaherty dp. Biochem Pharmacol. 2024 Oct;228:116160. doi: 10.1016/j.bcp.2024.116160. Epub 2024 Mar 24. Biochem Pharmacol. 2024. PMID: 38522554 Review.
59 results