Nussinov R - Search Results

1

Slower CDK4 and faster CDK2 activation in the cell cycle.

Zhang W, Liu Y, Jang H, Nussinov R. Zhang W, et al. Among authors: nussinov r. Structure. 2024 Aug 8;32(8):1269-1280.e2. doi: 10.1016/j.str.2024.04.012. Epub 2024 May 3. Structure. 2024. PMID: 38703777

2

How PTEN mutations degrade function at the membrane and life expectancy of carriers of mutations in the human brain.

Jang H, Chen J, Iakoucheva LM, Nussinov R. Jang H, et al. Among authors: nussinov r. bioRxiv [Preprint]. 2023 Jan 27:2023.01.26.525746. doi: 10.1101/2023.01.26.525746. bioRxiv. 2023. Update in: J Mol Biol. 2023 Dec 15;435(24):168354. doi: 10.1016/j.jmb.2023.168354 PMID: 36747841 Free PMC article. Updated. Preprint.

3

Cell cycle progression mechanisms: slower cyclin-D/CDK4 activation and faster cyclin-E/CDK2.

Zhang W, Liu Y, Jang H, Nussinov R. Zhang W, et al. Among authors: nussinov r. bioRxiv [Preprint]. 2023 Aug 17:2023.08.16.553605. doi: 10.1101/2023.08.16.553605. bioRxiv. 2023. PMID: 37790340 Free PMC article. Preprint.

4

Anticancer drugs: How to select small molecule combinations?

Nussinov R, Yavuz BR, Jang H. Nussinov R, et al. Trends Pharmacol Sci. 2024 Jun;45(6):503-519. doi: 10.1016/j.tips.2024.04.012. Epub 2024 May 22. Trends Pharmacol Sci. 2024. PMID: 38782689 Review.

5

Single cell spatial biology over developmental time can decipher pediatric brain pathologies.

Nussinov R, Yavuz BR, Jang H. Nussinov R, et al. Neurobiol Dis. 2024 Sep;199:106597. doi: 10.1016/j.nbd.2024.106597. Epub 2024 Jul 9. Neurobiol Dis. 2024. PMID: 38992777 Free article. Review.

6

Review: Cancer and neurodevelopmental disorders: multi-scale reasoning and computational guide.

Nussinov R, Yavuz BR, Demirel HC, Arici MK, Jang H, Tuncbag N. Nussinov R, et al. Front Cell Dev Biol. 2024 Jul 2;12:1376639. doi: 10.3389/fcell.2024.1376639. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 39015651 Free PMC article. Review.

7

Ras, RhoA, and vascular pharmacology in neurodevelopment and aging.

Nussinov R, Jang H, Cheng F. Nussinov R, et al. Neurochem Int. 2024 Dec;181:105883. doi: 10.1016/j.neuint.2024.105883. Epub 2024 Oct 18. Neurochem Int. 2024. PMID: 39427854 Review.

8

Directions to overcome therapy resistance in cancer.

Nussinov R, Weichhart T, Dlamini Z, Gibbons DL, Van Seuningen I, Konen J, Ju HQ. Nussinov R, et al. Trends Pharmacol Sci. 2024 Jun;45(6):467-471. doi: 10.1016/j.tips.2024.05.001. Epub 2024 May 16. Trends Pharmacol Sci. 2024. PMID: 38760267 No abstract available.

9

Accurate prediction of molecular targets using a self-supervised image representation learning framework.

Zeng X, Xiang H, Yu L, Wang J, Li K, Nussinov R, Cheng F. Zeng X, et al. Among authors: nussinov r. Res Sq [Preprint]. 2022 Apr 7:rs.3.rs-1477870. doi: 10.21203/rs.3.rs-1477870/v1. Res Sq. 2022. PMID: 35411337 Free PMC article. Updated. Preprint.

10

Systematic characterization of multi-omics landscape between gut microbial metabolites and GPCRome in Alzheimer's disease.

Qiu Y, Hou Y, Gohel D, Zhou Y, Xu J, Bykova M, Yang Y, Leverenz JB, Pieper AA, Nussinov R, Caldwell JZK, Brown JM, Cheng F. Qiu Y, et al. Among authors: nussinov r. Cell Rep. 2024 May 28;43(5):114128. doi: 10.1016/j.celrep.2024.114128. Epub 2024 Apr 21. Cell Rep. 2024. PMID: 38652661 Free article.

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