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Targeting pathological cells with senolytic drugs reduces seizures in neurodevelopmental mTOR-related epilepsy.
Ribierre T, Bacq A, Donneger F, Doladilhe M, Maletic M, Roussel D, Le Roux I, Chassoux F, Devaux B, Adle-Biassette H, Ferrand-Sorbets S, Dorfmüller G, Chipaux M, Baldassari S, Poncer JC, Baulac S. Ribierre T, et al. Among authors: bacq a. Nat Neurosci. 2024 Jun;27(6):1125-1136. doi: 10.1038/s41593-024-01634-2. Epub 2024 May 6. Nat Neurosci. 2024. PMID: 38710875 Free PMC article.
Targeted suppression of mTORC2 reduces seizures across models of epilepsy.
Okoh J, Mays J, Bacq A, Oses-Prieto JA, Tyanova S, Chen CJ, Imanbeyev K, Doladilhe M, Zhou H, Jafar-Nejad P, Burlingame A, Noebels J, Baulac S, Costa-Mattioli M. Okoh J, et al. Among authors: bacq a. Nat Commun. 2023 Nov 14;14(1):7364. doi: 10.1038/s41467-023-42922-y. Nat Commun. 2023. PMID: 37963879 Free PMC article.
Cardiac Investigations in Sudden Unexpected Death in DEPDC5-Related Epilepsy.
Bacq A, Roussel D, Bonduelle T, Zagaglia S, Maletic M, Ribierre T, Adle-Biassette H, Marchal C, Jennesson M, An I; Genomics England Research Consortium; Picard F, Navarro V, Sisodiya SM, Baulac S. Bacq A, et al. Ann Neurol. 2022 Jan;91(1):101-116. doi: 10.1002/ana.26256. Epub 2021 Nov 16. Ann Neurol. 2022. PMID: 34693554 Free PMC article.
LPA1 receptor and chronic stress: Effects on behaviour and the genes involved in the hippocampal excitatory/inhibitory balance.
Moreno-Fernández RD, Rosell-Valle C, Bacq A, Zanoletti O, Cifuentes M, Pérez-Martín M, Gavito AL, García-Fernández MI, Estivill-Torrús G, Rodríguez de Fonseca F, Santín LJ, Sandi C, Pedraza C. Moreno-Fernández RD, et al. Among authors: bacq a. Neuropharmacology. 2020 Mar 1;164:107896. doi: 10.1016/j.neuropharm.2019.107896. Epub 2019 Dec 4. Neuropharmacology. 2020. PMID: 31811875
14 results