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Page 1
De novo designed proteins neutralize lethal snake venom toxins.
Vázquez Torres S, Benard Valle M, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Vázquez Torres S, et al. Among authors: decarreau j. Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08393-x. Online ahead of print. Nature. 2025. PMID: 39814879
Computational design of bifaceted protein nanomaterials.
Rankovic S, Carr KD, Decarreau J, Skotheim R, Kibler RD, Ols S, Lee S, Chun JH, Tooley MR, Dauparas J, Eisenach HE, Glögl M, Weidle C, Borst AJ, Baker D, King NP. Rankovic S, et al. Among authors: decarreau j. bioRxiv [Preprint]. 2024 Dec 21:2024.10.18.619149. doi: 10.1101/2024.10.18.619149. bioRxiv. 2024. PMID: 39484564 Free PMC article. Preprint.
Diffusing protein binders to intrinsically disordered proteins.
Liu C, Wu K, Choi H, Han H, Zhang X, Watson JL, Shijo S, Bera AK, Kang A, Brackenbrough E, Coventry B, Hick DR, Hoofnagle AN, Zhu P, Li X, Decarreau J, Gerben SR, Yang W, Wang X, Lamp M, Murray A, Bauer M, Baker D. Liu C, et al. Among authors: decarreau j. bioRxiv [Preprint]. 2024 Jul 16:2024.07.16.603789. doi: 10.1101/2024.07.16.603789. bioRxiv. 2024. PMID: 39071267 Free PMC article. Preprint.
De novo designed proteins neutralize lethal snake venom toxins.
Torres SV, Valle MB, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Torres SV, et al. Among authors: decarreau j. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. PMID: 38798548 Free PMC article. Preprint.
Computational design of non-porous pH-responsive antibody nanoparticles.
Yang EC, Divine R, Miranda MC, Borst AJ, Sheffler W, Zhang JZ, Decarreau J, Saragovi A, Abedi M, Goldbach N, Ahlrichs M, Dobbins C, Hand A, Cheng S, Lamb M, Levine PM, Chan S, Skotheim R, Fallas J, Ueda G, Lubner J, Somiya M, Khmelinskaia A, King NP, Baker D. Yang EC, et al. Among authors: decarreau j. Nat Struct Mol Biol. 2024 Sep;31(9):1404-1412. doi: 10.1038/s41594-024-01288-5. Epub 2024 May 9. Nat Struct Mol Biol. 2024. PMID: 38724718 Free PMC article.
De novo design of pH-responsive self-assembling helical protein filaments.
Shen H, Lynch EM, Akkineni S, Watson JL, Decarreau J, Bethel NP, Benna I, Sheffler W, Farrell D, DiMaio F, Derivery E, De Yoreo JJ, Kollman J, Baker D. Shen H, et al. Among authors: decarreau j. Nat Nanotechnol. 2024 Jul;19(7):1016-1021. doi: 10.1038/s41565-024-01641-1. Epub 2024 Apr 3. Nat Nanotechnol. 2024. PMID: 38570702 Free PMC article.
Design of amyloidogenic peptide traps.
Sahtoe DD, Andrzejewska EA, Han HL, Rennella E, Schneider MM, Meisl G, Ahlrichs M, Decarreau J, Nguyen H, Kang A, Levine P, Lamb M, Li X, Bera AK, Kay LE, Knowles TPJ, Baker D. Sahtoe DD, et al. Among authors: decarreau j. Nat Chem Biol. 2024 Aug;20(8):981-990. doi: 10.1038/s41589-024-01578-5. Epub 2024 Mar 19. Nat Chem Biol. 2024. PMID: 38503834 Free PMC article.
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity.
Mout R, Bretherton RC, Decarreau J, Lee S, Gregorio N, Edman NI, Ahlrichs M, Hsia Y, Sahtoe DD, Ueda G, Sharma A, Schulman R, DeForest CA, Baker D. Mout R, et al. Among authors: decarreau j. Proc Natl Acad Sci U S A. 2024 Feb 6;121(6):e2309457121. doi: 10.1073/pnas.2309457121. Epub 2024 Jan 30. Proc Natl Acad Sci U S A. 2024. PMID: 38289949 Free PMC article.
In vivo selection of synthetic nucleocapsids for tissue targeting.
Olshefsky A, Benasutti H, Sylvestre M, Butterfield GL, Rocklin GJ, Richardson C, Hicks DR, Lajoie MJ, Song K, Leaf E, Treichel C, Decarreau J, Ke S, Kher G, Carter L, Chamberlain JS, Baker D, King NP, Pun SH. Olshefsky A, et al. Among authors: decarreau j. Proc Natl Acad Sci U S A. 2023 Nov 14;120(46):e2306129120. doi: 10.1073/pnas.2306129120. Epub 2023 Nov 8. Proc Natl Acad Sci U S A. 2023. PMID: 37939083 Free PMC article.
25 results