Hoffmann R - Search Results

1

Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88.

Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmüller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R. Lauer SM, et al. Among authors: hoffmann r. Nat Commun. 2024 May 10;15(1):3945. doi: 10.1038/s41467-024-48027-4. Nat Commun. 2024. PMID: 38730238 Free PMC article.

2

Sequence analysis of antimicrobial peptides by tandem mass spectrometry.

Stegemann C, Hoffmann R. Stegemann C, et al. Among authors: hoffmann r. Methods Mol Biol. 2008;494:31-46. doi: 10.1007/978-1-59745-419-3_3. Methods Mol Biol. 2008. PMID: 18726567

3

Effect of antimicrobial peptides from Apis mellifera hemolymph and its optimized version Api88 on biological activities of human monocytes and mast cells.

Keitel U, Schilling E, Knappe D, Al-Mekhlafi M, Petersen F, Hoffmann R, Hauschildt S. Keitel U, et al. Among authors: hoffmann r. Innate Immun. 2013;19(4):355-67. doi: 10.1177/1753425912462045. Epub 2012 Oct 30. Innate Immun. 2013. PMID: 23112010 Free article.

4

Novel apidaecin 1b analogs with superior serum stabilities for treatment of infections by gram-negative pathogens.

Berthold N, Czihal P, Fritsche S, Sauer U, Schiffer G, Knappe D, Alber G, Hoffmann R. Berthold N, et al. Among authors: hoffmann r. Antimicrob Agents Chemother. 2013 Jan;57(1):402-9. doi: 10.1128/AAC.01923-12. Epub 2012 Oct 31. Antimicrob Agents Chemother. 2013. PMID: 23114765 Free PMC article.

5

Insect-derived proline-rich antimicrobial peptides kill bacteria by inhibiting bacterial protein translation at the 70S ribosome.

Krizsan A, Volke D, Weinert S, Sträter N, Knappe D, Hoffmann R. Krizsan A, et al. Among authors: hoffmann r. Angew Chem Int Ed Engl. 2014 Nov 3;53(45):12236-9. doi: 10.1002/anie.201407145. Epub 2014 Sep 12. Angew Chem Int Ed Engl. 2014. PMID: 25220491

6

Influence of the yjiL-mdtM Gene Cluster on the Antibacterial Activity of Proline-Rich Antimicrobial Peptides Overcoming Escherichia coli Resistance Induced by the Missing SbmA Transporter System.

Krizsan A, Knappe D, Hoffmann R. Krizsan A, et al. Among authors: hoffmann r. Antimicrob Agents Chemother. 2015 Oct;59(10):5992-8. doi: 10.1128/AAC.01307-15. Epub 2015 Jul 13. Antimicrob Agents Chemother. 2015. PMID: 26169420 Free PMC article.

7

Identification of Api88 Binding Partners in Escherichia coli Using a Photoaffinity-Cross-Link Strategy and Label-Free Quantification.

Volke D, Krizsan A, Berthold N, Knappe D, Hoffmann R. Volke D, et al. Among authors: hoffmann r. J Proteome Res. 2015 Aug 7;14(8):3274-83. doi: 10.1021/acs.jproteome.5b00283. Epub 2015 Jul 21. J Proteome Res. 2015. PMID: 26196380

8

Immunogenicity and pharmacokinetics of short, proline-rich antimicrobial peptides.

Holfeld L, Herth N, Singer D, Hoffmann R, Knappe D. Holfeld L, et al. Among authors: hoffmann r. Future Med Chem. 2015 Aug;7(12):1581-96. doi: 10.4155/fmc.15.91. Epub 2015 Aug 26. Future Med Chem. 2015. PMID: 26308283

9

Structure-activity relationship study using peptide arrays to optimize Api137 for an increased antimicrobial activity against Pseudomonas aeruginosa.

Bluhm ME, Knappe D, Hoffmann R. Bluhm ME, et al. Among authors: hoffmann r. Eur J Med Chem. 2015 Oct 20;103:574-82. doi: 10.1016/j.ejmech.2015.09.022. Epub 2015 Sep 16. Eur J Med Chem. 2015. PMID: 26408816

10

Short Proline-Rich Antimicrobial Peptides Inhibit Either the Bacterial 70S Ribosome or the Assembly of its Large 50S Subunit.

Krizsan A, Prahl C, Goldbach T, Knappe D, Hoffmann R. Krizsan A, et al. Among authors: hoffmann r. Chembiochem. 2015 Nov 2;16(16):2304-8. doi: 10.1002/cbic.201500375. Epub 2015 Oct 8. Chembiochem. 2015. PMID: 26448548

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