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Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment.
Mathews RJ, Robinson JI, Battellino M, Wong C, Taylor JC; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate (BRAGGSS); Eyre S, Churchman SM, Wilson AG, Isaacs JD, Hyrich K, Barton A, Plant D, Savic S, Cook GP, Sarzi-Puttini P, Emery P, Barrett JH, Morgan AW, McDermott MF. Mathews RJ, et al. Among authors: plant d. Ann Rheum Dis. 2014 Jun;73(6):1202-10. doi: 10.1136/annrheumdis-2013-203276. Epub 2013 May 17. Ann Rheum Dis. 2014. PMID: 23687262
Association of chemokine CXC ligand 12 gene polymorphism (rs1746048) with cardiovascular mortality in patients with rheumatoid arthritis: results from the Norfolk Arthritis Register.
Ibrahim I, Humphreys J, Mokhtar I, Marshall T, Verstappen S, Symmons D, Viatte S, Barton A, Plant D. Ibrahim I, et al. Among authors: plant d. Ann Rheum Dis. 2015 Nov;74(11):2099-102. doi: 10.1136/annrheumdis-2015-207851. Epub 2015 Aug 31. Ann Rheum Dis. 2015. PMID: 26324845 No abstract available.
Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39.
Spiliopoulou A, Colombo M, Plant D, Nair N, Cui J, Coenen MJ, Ikari K, Yamanaka H, Saevarsdottir S, Padyukov L, Bridges SL Jr, Kimberly RP, Okada Y, van Riel PLC, Wolbink G, van der Horst-Bruinsma IE, de Vries N, Tak PP, Ohmura K, Canhão H, Guchelaar HJ, Huizinga TW, Criswell LA, Raychaudhuri S, Weinblatt ME, Wilson AG, Mariette X, Isaacs JD, Morgan AW, Pitzalis C, Barton A, McKeigue P. Spiliopoulou A, et al. Among authors: plant d. Ann Rheum Dis. 2019 Aug;78(8):1055-1061. doi: 10.1136/annrheumdis-2018-214877. Epub 2019 Apr 29. Ann Rheum Dis. 2019. PMID: 31036624 Free PMC article.
Investigation of genetically regulated gene expression and response to treatment in rheumatoid arthritis highlights an association between IL18RAP expression and treatment response.
Cherlin S, Lewis MJ, Plant D, Nair N, Goldmann K, Tzanis E, Barnes MR, McKeigue P, Barrett JH, Pitzalis C, Barton A; MATURA Consortium; Cordell HJ. Cherlin S, et al. Among authors: plant d. Ann Rheum Dis. 2020 Nov;79(11):1446-1452. doi: 10.1136/annrheumdis-2020-217204. Epub 2020 Jul 30. Ann Rheum Dis. 2020. PMID: 32732242 Free PMC article.
Comprehensive genetic and functional analyses of Fc gamma receptors influence on response to rituximab therapy for autoimmunity.
Robinson JI, Md Yusof MY, Davies V, Wild D, Morgan M, Taylor JC, El-Sherbiny Y, Morris DL, Liu L, Rawstron AC, Buch MH, Plant D, Cordell HJ, Isaacs JD, Bruce IN, Emery P, Barton A, Vyse TJ, Barrett JH, Vital EM, Morgan AW; MATURA Consortia; MASTERPLANS Consortia. Robinson JI, et al. Among authors: plant d. EBioMedicine. 2022 Dec;86:104343. doi: 10.1016/j.ebiom.2022.104343. Epub 2022 Nov 11. EBioMedicine. 2022. PMID: 36371989 Free PMC article.
Pre-treatment calprotectin (MRP8/14) provides no added value to testing CRP alone in terms of predicting response to TNF inhibitors in rheumatoid arthritis in a post hoc analysis.
Smith SL, Alexander S, Nair N, Viatte S, Eyre S, Hyrich KL, Morgan AW, Wilson AG, Isaacs JD, Plant D, Barton A. Smith SL, et al. Among authors: plant d. Ann Rheum Dis. 2023 May;82(5):611-620. doi: 10.1136/ard-2022-222519. Epub 2023 Feb 21. Ann Rheum Dis. 2023. PMID: 36810200 Free PMC article.
Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis.
Ho PY, Barton A, Worthington J, Plant D, Griffiths CE, Young HS, Bradburn P, Thomson W, Silman AJ, Bruce IN. Ho PY, et al. Among authors: plant d. Ann Rheum Dis. 2008 May;67(5):677-82. doi: 10.1136/ard.2007.071399. Epub 2007 Aug 29. Ann Rheum Dis. 2008. PMID: 17728335 Free PMC article.
324 results