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l-2-Hydroxyglutarate remodeling of the epigenome and epitranscriptome creates a metabolic vulnerability in kidney cancer models.
Kundu A, Brinkley GJ, Nam H, Karki S, Kirkman R, Pandit M, Shim E, Widden H, Liu J, Heidarian Y, Mahmoudzadeh NH, Fitt AJ, Absher D, Ding HF, Crossman DK, Placzek WJ, Locasale JW, Rakheja D, McConathy JE, Ramachandran R, Bae S, Tennessen JM, Sudarshan S. Kundu A, et al. Among authors: nam h. J Clin Invest. 2024 May 14;134(13):e171294. doi: 10.1172/JCI171294. J Clin Invest. 2024. PMID: 38743486 Free PMC article.
Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidney.
Brinkley G, Nam H, Shim E, Kirkman R, Kundu A, Karki S, Heidarian Y, Tennessen JM, Liu J, Locasale JW, Guo T, Wei S, Gordetsky J, Johnson-Pais TL, Absher D, Rakheja D, Challa AK, Sudarshan S. Brinkley G, et al. Among authors: nam h. Dis Model Mech. 2020 Nov 27;13(11):dmm045898. doi: 10.1242/dmm.045898. Dis Model Mech. 2020. PMID: 32928875 Free PMC article.
The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancer.
Nam H, Kundu A, Karki S, Brinkley GJ, Chandrashekar DS, Kirkman RL, Liu J, Liberti MV, Locasale JW, Mitchell T, Varambally S, Sudarshan S. Nam H, et al. JCI Insight. 2021 Nov 22;6(22):e148438. doi: 10.1172/jci.insight.148438. JCI Insight. 2021. PMID: 34609963 Free PMC article.
PRDM16 suppresses HIF-targeted gene expression in kidney cancer.
Kundu A, Nam H, Shelar S, Chandrashekar DS, Brinkley G, Karki S, Mitchell T, Livi CB, Buckhaults P, Kirkman R, Tang Y, Rowe GC, Wei S, Varambally S, Sudarshan S. Kundu A, et al. Among authors: nam h. J Exp Med. 2020 Jun 1;217(6):e20191005. doi: 10.1084/jem.20191005. J Exp Med. 2020. PMID: 32251515 Free PMC article.
Deciphering Dysfunctional Regulatory T Cells in Atopic Dermatitis.
Kang SJ, Gong JR, Jin SP, Oh JM, Jin H, Lee Y, Moon Y, Kim D, Nam HJ, Choi HS, Hwang S, Huh YJ, Han KY, Moon J, Chung J, Park WY, Park CG, Kim HJ, Kim JE. Kang SJ, et al. Among authors: nam hj. Allergy. 2024 Dec 18. doi: 10.1111/all.16439. Online ahead of print. Allergy. 2024. PMID: 39692151 No abstract available.
2,628 results