Dash RC - Search Results

1

Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction.

Zaino AM, Dash RC, James SJ, MacGilvary N, Crompton A, McPherson KS, Stanzione M, Korzhnev DM, Dyson NJ, Chatterjee N, Cantor SB, Hadden MK. Zaino AM, et al. Among authors: dash rc. Bioorg Med Chem. 2024 May 15;106:117755. doi: 10.1016/j.bmc.2024.117755. Epub 2024 May 9. Bioorg Med Chem. 2024. PMID: 38749343

2

A molecular dynamics approach to identify an oxysterol-based hedgehog pathway inhibitor.

Dash RC, Maschinot CR, Hadden MK. Dash RC, et al. Biochim Biophys Acta Gen Subj. 2017 Feb;1861(2):168-177. doi: 10.1016/j.bbagen.2016.11.003. Epub 2016 Nov 5. Biochim Biophys Acta Gen Subj. 2017. PMID: 27825830

3

Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction.

Sail V, Rizzo AA, Chatterjee N, Dash RC, Ozen Z, Walker GC, Korzhnev DM, Hadden MK. Sail V, et al. Among authors: dash rc. ACS Chem Biol. 2017 Jul 21;12(7):1903-1912. doi: 10.1021/acschembio.6b01144. Epub 2017 Jun 9. ACS Chem Biol. 2017. PMID: 28541665 Free PMC article.

4

A metadynamic approach to understand the recognition mechanism of the histone H3 tail with the ATRX_ADD domain.

Dash RC, Zaino AM, Hadden MK. Dash RC, et al. Biochim Biophys Acta Gene Regul Mech. 2018 Jun;1861(6):594-602. doi: 10.1016/j.bbagrm.2018.05.001. Epub 2018 May 3. Biochim Biophys Acta Gene Regul Mech. 2018. PMID: 29730439

5

Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction.

Ozen Z, Dash RC, McCarthy KR, Chow SA, Rizzo AA, Korzhnev DM, Hadden MK. Ozen Z, et al. Among authors: dash rc. Bioorg Med Chem. 2018 Aug 7;26(14):4301-4309. doi: 10.1016/j.bmc.2018.07.029. Epub 2018 Jul 19. Bioorg Med Chem. 2018. PMID: 30037752

6

Structural Approach To Identify a Lead Scaffold That Targets the Translesion Synthesis Polymerase Rev1.

Dash RC, Ozen Z, Rizzo AA, Lim S, Korzhnev DM, Hadden MK. Dash RC, et al. J Chem Inf Model. 2018 Nov 26;58(11):2266-2277. doi: 10.1021/acs.jcim.8b00535. Epub 2018 Oct 19. J Chem Inf Model. 2018. PMID: 30289707

7

Development of posaconazole-based analogues as hedgehog signaling pathway inhibitors.

Teske KA, Dash RC, Morel SR, Chau LQ, Wechsler-Reya RJ, Hadden MK. Teske KA, et al. Among authors: dash rc. Eur J Med Chem. 2019 Feb 1;163:320-332. doi: 10.1016/j.ejmech.2018.11.056. Epub 2018 Nov 23. Eur J Med Chem. 2019. PMID: 30529635 Free PMC article.

8

Structure-Activity Relationships for Itraconazole-Based Triazolone Analogues as Hedgehog Pathway Inhibitors.

Pace JR, Teske KA, Chau LQ, Dash RC, Zaino AM, Wechsler-Reya RJ, Hadden MK. Pace JR, et al. Among authors: dash rc. J Med Chem. 2019 Apr 25;62(8):3873-3885. doi: 10.1021/acs.jmedchem.8b01283. Epub 2019 Apr 5. J Med Chem. 2019. PMID: 30896941 Free PMC article.

9

Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Protein Interaction.

Dash RC, Ozen Z, McCarthy KR, Chatterjee N, Harris CA, Rizzo AA, Walker GC, Korzhnev DM, Hadden MK. Dash RC, et al. ChemMedChem. 2019 Sep 4;14(17):1610-1617. doi: 10.1002/cmdc.201900307. Epub 2019 Aug 21. ChemMedChem. 2019. PMID: 31361935 Free PMC article.

10

Probing the Protein-Protein Interaction Between the ATRX_ADD Domain and the Histone H3 Tail.

Zaino AM, Dash RC, Hadden MK. Zaino AM, et al. Among authors: dash rc. Molecules. 2020 Mar 25;25(7):1500. doi: 10.3390/molecules25071500. Molecules. 2020. PMID: 32218364 Free PMC article.

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