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Blood brain barrier disruption and glutamatergic excitotoxicity in post-acute sequelae of SARS COV-2 infection cognitive impairment: potential biomarkers and a window into pathogenesis.
Chaganti J, Poudel G, Cysique LA, Dore GJ, Kelleher A, Matthews G, Darley D, Byrne A, Jakabek D, Zhang X, Lewis M, Jha N, Brew BJ. Chaganti J, et al. Among authors: darley d. Front Neurol. 2024 May 2;15:1350848. doi: 10.3389/fneur.2024.1350848. eCollection 2024. Front Neurol. 2024. PMID: 38756214 Free PMC article.
Platform for isolation and characterization of SARS-CoV-2 variants enables rapid characterization of Omicron in Australia.
Aggarwal A, Stella AO, Walker G, Akerman A, Esneau C, Milogiannakis V, Burnett DL, McAllery S, Silva MR, Lu Y, Foster CSP, Brilot F, Pillay A, Van Hal S, Mathivanan V, Fichter C, Kindinger A, Hoppe AC, Munier ML, Amatayakul-Chantler S, Roth N, Coppola G, Symonds GP, Schofield P, Jackson J, Lenthall H, Henry JY, Mazigi O, Jäck HM, Davenport MP, Darley DR, Matthews GV, Khoury DS, Cromer D, Goodnow CC, Christ D, Robosa R, Starck DJ, Bartlett NW, Rawlinson WD, Kelleher AD, Turville SG. Aggarwal A, et al. Among authors: darley dr. Nat Microbiol. 2022 Jun;7(6):896-908. doi: 10.1038/s41564-022-01135-7. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637329 Free PMC article.
High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells.
Phetsouphanh C, Khoo WH, Jackson K, Klemm V, Howe A, Aggarwal A, Akerman A, Milogiannakis V, Stella AO, Rouet R, Schofield P, Faulks ML, Law H, Danwilai T, Starr M, Munier CML, Christ D, Singh M, Croucher PI, Brilot-Turville F, Turville S, Phan TG, Dore GJ, Darley D, Cunningham P, Matthews GV, Kelleher AD, Zaunders JJ. Phetsouphanh C, et al. Among authors: darley d. Front Immunol. 2022 Dec 5;13:1032911. doi: 10.3389/fimmu.2022.1032911. eCollection 2022. Front Immunol. 2022. PMID: 36544780 Free PMC article.
The kynurenine pathway relates to post-acute COVID-19 objective cognitive impairment and PASC.
Cysique LA, Jakabek D, Bracken SG, Allen-Davidian Y, Heng B, Chow S, Dehhaghi M, Staats Pires A, Darley DR, Byrne A, Phetsouphanh C, Kelleher A, Dore GJ, Matthews GV, Guillemin GJ, Brew BJ. Cysique LA, et al. Among authors: darley dr. Ann Clin Transl Neurol. 2023 Aug;10(8):1338-1352. doi: 10.1002/acn3.51825. Epub 2023 Jun 15. Ann Clin Transl Neurol. 2023. PMID: 37318955 Free PMC article.
Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection.
Phetsouphanh C, Jacka B, Ballouz S, Jackson KJL, Wilson DB, Manandhar B, Klemm V, Tan HX, Wheatley A, Aggarwal A, Akerman A, Milogiannakis V, Starr M, Cunningham P, Turville SG, Kent SJ, Byrne A, Brew BJ, Darley DR, Dore GJ, Kelleher AD, Matthews GV. Phetsouphanh C, et al. Among authors: darley dr. Nat Commun. 2024 Apr 17;15(1):3315. doi: 10.1038/s41467-024-47720-8. Nat Commun. 2024. PMID: 38632311 Free PMC article.
51 results