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Page 1
Rigor and reproducibility in human brain organoid research: Where we are and where we need to go.
Sandoval SO, Cappuccio G, Kruth K, Osenberg S, Khalil SM, Méndez-Albelo NM, Padmanabhan K, Wang D, Niciu MJ, Bhattacharyya A, Stein JL, Sousa AMM, Waxman EA, Buttermore ED, Whye D, Sirois CL; Cross-IDDRC Human Stem Cell Consortium; Williams A, Maletic-Savatic M, Zhao X. Sandoval SO, et al. Among authors: sirois cl. Stem Cell Reports. 2024 Jun 11;19(6):796-816. doi: 10.1016/j.stemcr.2024.04.008. Epub 2024 May 16. Stem Cell Reports. 2024. PMID: 38759644 Free PMC article. Review.
Transcriptional consequences of trisomy 21 on neural induction.
Martinez JL, Piciw JG, Crockett M, Sorci IA, Makwana N, Sirois CL, Giffin-Rao Y, Bhattacharyya A. Martinez JL, et al. Among authors: sirois cl. Front Cell Neurosci. 2024 Jan 30;18:1341141. doi: 10.3389/fncel.2024.1341141. eCollection 2024. Front Cell Neurosci. 2024. PMID: 38357436 Free PMC article.
FMRP gains mitochondrial fission control.
Sirois CL, Sandoval SO, Zhao X. Sirois CL, et al. Nat Cell Biol. 2024 Dec;26(12):2014-2015. doi: 10.1038/s41556-024-01567-9. Nat Cell Biol. 2024. PMID: 39548328 No abstract available.
Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development.
Shen M, Sirois CL, Guo Y, Li M, Dong Q, Méndez-Albelo NM, Gao Y, Khullar S, Kissel L, Sandoval SO, Wolkoff NE, Huang SX, Xu Z, Bryan JE, Contractor AM, Korabelnikov T, Glass IA, Doherty D; Birth Defects Research Laboratory; Levine JE, Sousa AMM, Chang Q, Bhattacharyya A, Wang D, Werling DM, Zhao X. Shen M, et al. Among authors: sirois cl. Neuron. 2023 Dec 20;111(24):3988-4005.e11. doi: 10.1016/j.neuron.2023.09.014. Epub 2023 Oct 10. Neuron. 2023. PMID: 37820724 Free PMC article.
Elevated levels of FMRP-target MAP1B impair human and mouse neuronal development and mouse social behaviors via autophagy pathway.
Guo Y, Shen M, Dong Q, Méndez-Albelo NM, Huang SX, Sirois CL, Le J, Li M, Jarzembowski ED, Schoeller KA, Stockton ME, Horner VL, Sousa AMM, Gao Y; Birth Defects Research Laboratory; Levine JE, Wang D, Chang Q, Zhao X. Guo Y, et al. Among authors: sirois cl. Nat Commun. 2023 Jun 26;14(1):3801. doi: 10.1038/s41467-023-39337-0. Nat Commun. 2023. PMID: 37365192 Free PMC article.
Abundance and localization of human UBE3A protein isoforms.
Sirois CL, Bloom JE, Fink JJ, Gorka D, Keller S, Germain ND, Levine ES, Chamberlain SJ. Sirois CL, et al. Hum Mol Genet. 2020 Nov 4;29(18):3021-3031. doi: 10.1093/hmg/ddaa191. Hum Mol Genet. 2020. PMID: 32833011 Free PMC article.
17 results