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Gut flora disequilibrium promotes the initiation of liver cancer by modulating tryptophan metabolism and up-regulating SREBP2.
Chen W, Wen L, Bao Y, Tang Z, Zhao J, Zhang X, Wei T, Zhang J, Ma T, Zhang Q, Zhi X, Li J, Zhang C, Ni L, Li M, Liang T. Chen W, et al. Among authors: zhang c, zhang q, zhang j, zhang x. Proc Natl Acad Sci U S A. 2022 Dec 27;119(52):e2203894119. doi: 10.1073/pnas.2203894119. Epub 2022 Dec 19. Proc Natl Acad Sci U S A. 2022. PMID: 36534812 Free PMC article.
Phase I study of MSB2311, a novel pH-dependent anti-PD-L1 monoclonal antibody, treating patients with advanced solid tumors and lymphoma.
Zhang Q, Zhang J, Zhong H, Yuan Y, Yang L, Zhang Q, Ji D, Gong J, Li J, Yao Z, Qi C, Wang J, Lu L, Shi M, Qian X, Shen L, Li J, Hu X. Zhang Q, et al. Among authors: zhang j. Cancer Immunol Immunother. 2023 Aug;72(8):2729-2739. doi: 10.1007/s00262-023-03434-2. Epub 2023 Apr 28. Cancer Immunol Immunother. 2023. PMID: 37115210 Free PMC article. Clinical Trial.
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