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Page 1
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models.
Hertz N, Chin R, Rakhit R, Ditsworth D, Wang C, Bartholomeus J, Liu S, Mody A, Laihsu A, Eastes A, Tai C, Kim R, Li J, Khasnavis S, Rafalski V, Heerendeen D, Garda V, Phung J, de Roulet D, Ordureau A, Harper JW, Johnstone S, Stöhr J. Hertz N, et al. Among authors: johnstone s. Res Sq [Preprint]. 2024 May 10:rs.3.rs-4356493. doi: 10.21203/rs.3.rs-4356493/v1. Res Sq. 2024. PMID: 38765977 Free PMC article. Preprint.
Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models.
Chin RM, Rakhit R, Ditsworth D, Wang C, Bartholomeus J, Liu S, Mody A, Laishu A, Eastes A, Tai C, Kim RY, Li J, Hansberry S, Khasnavis S, Rafalski V, Herendeen D, Garda V, Phung J, de Roulet D, Ordureau A, Harper JW, Johnstone S, Stöhr J, Hertz NT. Chin RM, et al. Among authors: johnstone s. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528378. doi: 10.1101/2023.02.14.528378. bioRxiv. 2023. PMID: 36824886 Free PMC article. Preprint.
Rational Design of Macrocyclic Noncovalent Inhibitors of SARS-CoV-2 Mpro from a DNA-Encoded Chemical Library Screening Hit That Demonstrate Potent Inhibition against Pan-Coronavirus Homologues and Nirmatrelvir-Resistant Variants.
Wang X, Gotchev D, Fan KY, Vega MM, Mani N, McGovern-Gooch K, Cuconati A, Tercero B, Wang X, Carpino P, Maskos K, Centrella PA, Schmitt A, Preuss F, Prasad A, Chen CY, Clark MA, Guilinger JP, Johnstone S, von König K, Keefe AD, Liu J, Turcotte S, Zhang Y, Konz Makino DL, Lam AM, Cole AG, Sofia MJ. Wang X, et al. Among authors: johnstone s. J Med Chem. 2024 Nov 14;67(21):19623-19667. doi: 10.1021/acs.jmedchem.4c02009. Epub 2024 Oct 25. J Med Chem. 2024. PMID: 39453309
Adeno-associated virus-mediated gene delivery of Perm1 enhances cardiac contractility in mice.
Sreedevi K, Zaitsev AV, Doku A, Thomas R, James A, Do S, Zhang M, Sedovy MW, Leng X, Dennison CL, Johnstone SR, Kirk JA, Yan Z, Warren JS. Sreedevi K, et al. Among authors: johnstone sr. Am J Physiol Heart Circ Physiol. 2024 Oct 1;327(4):H1112-H1118. doi: 10.1152/ajpheart.00545.2024. Epub 2024 Sep 13. Am J Physiol Heart Circ Physiol. 2024. PMID: 39269449
Endothelial-adipocyte Cx43 Mediated Gap Junctions Can Regulate Adiposity.
Luse MA, Dunaway LS, Nyshadham S, Carvalho A, Sedovy MW, Ruddiman CA, Tessema R, Hirschi K, Johnstone SR, Isakson BE. Luse MA, et al. Among authors: johnstone sr. Function (Oxf). 2024 Sep 10;5(5):zqae029. doi: 10.1093/function/zqae029. Function (Oxf). 2024. PMID: 38984993 Free PMC article.
369 results