Niessen KV - Search Results

1

Identification of ligands binding to MB327-PAM-1, a binding pocket relevant for resensitization of nAChRs.

Kaiser J, Gertzen CGW, Bernauer T, Nitsche V, Höfner G, Niessen KV, Seeger T, Paintner FF, Wanner KT, Steinritz D, Worek F, Gohlke H. Kaiser J, et al. Among authors: niessen kv. Toxicol Lett. 2024 Jul;398:91-104. doi: 10.1016/j.toxlet.2024.05.013. Epub 2024 May 18. Toxicol Lett. 2024. PMID: 38768836 Free article.

2

Competitive MS binding assays for dopamine D2 receptors employing spiperone as a native marker.

Niessen KV, Höfner G, Wanner KT. Niessen KV, et al. Chembiochem. 2005 Oct;6(10):1769-75. doi: 10.1002/cbic.200500074. Chembiochem. 2005. PMID: 16149041

3

Interaction of bispyridinium compounds with the orthosteric binding site of human α7 and Torpedo californica nicotinic acetylcholine receptors (nAChRs).

Niessen KV, Tattersall JE, Timperley CM, Bird M, Green C, Seeger T, Thiermann H, Worek F. Niessen KV, et al. Toxicol Lett. 2011 Sep 25;206(1):100-4. doi: 10.1016/j.toxlet.2011.06.009. Epub 2011 Jun 16. Toxicol Lett. 2011. PMID: 21703337

4

Restoration of nerve agent inhibited muscle force production in human intercostal muscle strips with HI 6.

Seeger T, Niessen KV, Langer P, Gerhardus J, Worek F, Friess H, Bumm R, Mihaljevic AL, Thiermann H. Seeger T, et al. Among authors: niessen kv. Toxicol Lett. 2011 Sep 25;206(1):72-6. doi: 10.1016/j.toxlet.2011.07.016. Epub 2011 Jul 23. Toxicol Lett. 2011. PMID: 21803135

5

Restoration of soman-blocked neuromuscular transmission in human and rat muscle by the bispyridinium non-oxime MB327 in vitro.

Seeger T, Eichhorn M, Lindner M, Niessen KV, Tattersall JE, Timperley CM, Bird M, Green AC, Thiermann H, Worek F. Seeger T, et al. Among authors: niessen kv. Toxicology. 2012 Apr 11;294(2-3):80-4. doi: 10.1016/j.tox.2012.02.002. Epub 2012 Feb 13. Toxicology. 2012. PMID: 22349640

6

Competition radioligand binding assays for the investigation of bispyridinium compound affinities to the human muscarinic acetylcholine receptor subtype 5 (hM(5) ).

Niessen KV, Tattersall JE, Timperley CM, Bird M, Green C, Thiermann H, Worek F. Niessen KV, et al. Drug Test Anal. 2012 Mar-Apr;4(3-4):292-7. doi: 10.1002/dta.410. Epub 2012 Feb 24. Drug Test Anal. 2012. PMID: 22362630

7

Affinities of bispyridinium non-oxime compounds to [(3)H]epibatidine binding sites of Torpedo californica nicotinic acetylcholine receptors depend on linker length.

Niessen KV, Seeger T, Tattersall JE, Timperley CM, Bird M, Green C, Thiermann H, Worek F. Niessen KV, et al. Chem Biol Interact. 2013 Dec 5;206(3):545-54. doi: 10.1016/j.cbi.2013.10.012. Epub 2013 Oct 21. Chem Biol Interact. 2013. PMID: 24157926

8

Functional analysis of Torpedo californica nicotinic acetylcholine receptors in multiple activation states by SSM-based electrophysiology.

Niessen KV, Muschik S, Langguth F, Rappenglück S, Seeger T, Thiermann H, Worek F. Niessen KV, et al. Toxicol Lett. 2016 Apr 15;247:1-10. doi: 10.1016/j.toxlet.2016.02.002. Epub 2016 Feb 3. Toxicol Lett. 2016. PMID: 26851639

9

In vitro pharmacological characterization of the bispyridinium non-oxime compound MB327 and its 2- and 3-regioisomers.

Niessen KV, Seeger T, Rappenglück S, Wein T, Höfner G, Wanner KT, Thiermann H, Worek F. Niessen KV, et al. Toxicol Lett. 2018 Sep 1;293:190-197. doi: 10.1016/j.toxlet.2017.10.009. Epub 2017 Oct 10. Toxicol Lett. 2018. PMID: 29024789

10

Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor.

Wein T, Höfner G, Rappenglück S, Sichler S, Niessen KV, Seeger T, Worek F, Thiermann H, Wanner KT. Wein T, et al. Among authors: niessen kv. Toxicol Lett. 2018 Sep 1;293:184-189. doi: 10.1016/j.toxlet.2017.10.024. Epub 2017 Oct 31. Toxicol Lett. 2018. PMID: 29097222

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