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Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Teixeira da Rosa N Jr, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML. Liang Z, et al. Among authors: hazime s. Sci Rep. 2024 May 20;14(1):11497. doi: 10.1038/s41598-024-62262-1. Sci Rep. 2024. PMID: 38769106 Free PMC article.
Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction and leads to increased glucose uptake in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML. Liang Z, et al. Among authors: hazime s. bioRxiv [Preprint]. 2024 Feb 4:2024.02.03.578755. doi: 10.1101/2024.02.03.578755. bioRxiv. 2024. Update in: Sci Rep. 2024 May 20;14(1):11497. doi: 10.1038/s41598-024-62262-1 PMID: 38352304 Free PMC article. Updated. Preprint.
Author Correction: Upregulation of the AMPK-FOXO1-PDK4 pathway is a primary mechanism of pyruvate dehydrogenase activity reduction in tafazzin-deficient cells.
Liang Z, Ralph-Epps T, Schmidtke MW, Lazcano P, Denis SW, Balážová M, Teixeira da Rosa N Jr, Chakkour M, Hazime S, Ren M, Schlame M, Houtkooper RH, Greenberg ML. Liang Z, et al. Among authors: hazime s. Sci Rep. 2024 Jun 25;14(1):14633. doi: 10.1038/s41598-024-65477-4. Sci Rep. 2024. PMID: 38918568 Free PMC article. No abstract available.