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Development of an analytical platform for the affinity screening of natural extracts by SEC-MS towards PPARα and PPARγ receptors.
De Soricellis G, Rinaldi F, Tengattini S, Temporini C, Negri S, Capelli D, Montanari R, Cena H, Salerno S, Massolini G, Guzzo F, Calleri E. De Soricellis G, et al. Among authors: capelli d. Anal Chim Acta. 2024 Jun 22;1309:342666. doi: 10.1016/j.aca.2024.342666. Epub 2024 May 4. Anal Chim Acta. 2024. PMID: 38772654 Free article.
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression.
Laghezza A, Pochetti G, Lavecchia A, Fracchiolla G, Faliti S, Piemontese L, Di Giovanni C, Iacobazzi V, Infantino V, Montanari R, Capelli D, Tortorella P, Loiodice F. Laghezza A, et al. Among authors: capelli d. J Med Chem. 2013 Jan 10;56(1):60-72. doi: 10.1021/jm301018z. Epub 2012 Dec 18. J Med Chem. 2013. PMID: 23171045
Resveratrol and its metabolites bind to PPARs.
Calleri E, Pochetti G, Dossou KSS, Laghezza A, Montanari R, Capelli D, Prada E, Loiodice F, Massolini G, Bernier M, Moaddel R. Calleri E, et al. Among authors: capelli d. Chembiochem. 2014 May 26;15(8):1154-1160. doi: 10.1002/cbic.201300754. Epub 2014 May 5. Chembiochem. 2014. PMID: 24796862 Free PMC article.
Structural basis of the transactivation deficiency of the human PPARγ F360L mutant associated with familial partial lipodystrophy.
Lori C, Pasquo A, Montanari R, Capelli D, Consalvi V, Chiaraluce R, Cervoni L, Loiodice F, Laghezza A, Aschi M, Giorgi A, Pochetti G. Lori C, et al. Among authors: capelli d. Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1965-76. doi: 10.1107/S1399004714009638. Epub 2014 Jun 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25004973
Identification of the First PPARα/γ Dual Agonist Able To Bind to Canonical and Alternative Sites of PPARγ and To Inhibit Its Cdk5-Mediated Phosphorylation.
Laghezza A, Piemontese L, Cerchia C, Montanari R, Capelli D, Giudici M, Crestani M, Tortorella P, Peiretti F, Pochetti G, Lavecchia A, Loiodice F. Laghezza A, et al. Among authors: capelli d. J Med Chem. 2018 Sep 27;61(18):8282-8298. doi: 10.1021/acs.jmedchem.8b00835. Epub 2018 Sep 18. J Med Chem. 2018. PMID: 30199253
Surface Plasmon Resonance as a Tool for Ligand Binding Investigation of Engineered GPR17 Receptor, a G Protein Coupled Receptor Involved in Myelination.
Capelli D, Parravicini C, Pochetti G, Montanari R, Temporini C, Rabuffetti M, Trincavelli ML, Daniele S, Fumagalli M, Saporiti S, Bonfanti E, Abbracchio MP, Eberini I, Ceruti S, Calleri E, Capaldi S. Capelli D, et al. Front Chem. 2020 Jan 10;7:910. doi: 10.3389/fchem.2019.00910. eCollection 2019. Front Chem. 2020. PMID: 31998697 Free PMC article.
Insights into PPARγ Phosphorylation and Its Inhibition Mechanism.
Montanari R, Capelli D, Yamamoto K, Awaishima H, Nishikata K, Barendregt A, Heck AJR, Loiodice F, Altieri F, Paiardini A, Grottesi A, Pirone L, Pedone E, Peiretti F, Brunel JM, Itoh T, Pochetti G. Montanari R, et al. Among authors: capelli d. J Med Chem. 2020 May 14;63(9):4811-4823. doi: 10.1021/acs.jmedchem.0c00048. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32239932 Free article.
68 results