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Page 1
Development of an analytical platform for the affinity screening of natural extracts by SEC-MS towards PPARα and PPARγ receptors.
De Soricellis G, Rinaldi F, Tengattini S, Temporini C, Negri S, Capelli D, Montanari R, Cena H, Salerno S, Massolini G, Guzzo F, Calleri E. De Soricellis G, et al. Among authors: montanari r. Anal Chim Acta. 2024 Jun 22;1309:342666. doi: 10.1016/j.aca.2024.342666. Epub 2024 May 4. Anal Chim Acta. 2024. PMID: 38772654 Free article.
Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity.
Porcelli L, Gilardi F, Laghezza A, Piemontese L, Mitro N, Azzariti A, Altieri F, Cervoni L, Fracchiolla G, Giudici M, Guerrini U, Lavecchia A, Montanari R, Di Giovanni C, Paradiso A, Pochetti G, Simone GM, Tortorella P, Crestani M, Loiodice F. Porcelli L, et al. Among authors: montanari r. J Med Chem. 2012 Jan 12;55(1):37-54. doi: 10.1021/jm201306q. Epub 2011 Dec 2. J Med Chem. 2012. PMID: 22081932
Structural insight into peroxisome proliferator-activated receptor gamma binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and site-directed mutagenesis.
Pochetti G, Mitro N, Lavecchia A, Gilardi F, Besker N, Scotti E, Aschi M, Re N, Fracchiolla G, Laghezza A, Tortorella P, Montanari R, Novellino E, Mazza F, Crestani M, Loiodice F. Pochetti G, et al. Among authors: montanari r. J Med Chem. 2010 Jun 10;53(11):4354-66. doi: 10.1021/jm9013899. J Med Chem. 2010. PMID: 20462215
New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function.
Fracchiolla G, Laghezza A, Piemontese L, Tortorella P, Mazza F, Montanari R, Pochetti G, Lavecchia A, Novellino E, Pierno S, Conte Camerino D, Loiodice F. Fracchiolla G, et al. Among authors: montanari r. J Med Chem. 2009 Oct 22;52(20):6382-93. doi: 10.1021/jm900941b. J Med Chem. 2009. PMID: 19775169
Frontal affinity chromatography with MS detection of the ligand binding domain of PPARγ receptor: ligand affinity screening and stereoselective ligand-macromolecule interaction.
Calleri E, Fracchiolla G, Montanari R, Pochetti G, Lavecchia A, Loiodice F, Laghezza A, Piemontese L, Massolini G, Temporini C. Calleri E, et al. Among authors: montanari r. J Chromatogr A. 2012 Apr 6;1232:84-92. doi: 10.1016/j.chroma.2011.10.037. Epub 2011 Oct 19. J Chromatogr A. 2012. PMID: 22056242
New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptor α/γ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression.
Laghezza A, Pochetti G, Lavecchia A, Fracchiolla G, Faliti S, Piemontese L, Di Giovanni C, Iacobazzi V, Infantino V, Montanari R, Capelli D, Tortorella P, Loiodice F. Laghezza A, et al. Among authors: montanari r. J Med Chem. 2013 Jan 10;56(1):60-72. doi: 10.1021/jm301018z. Epub 2012 Dec 18. J Med Chem. 2013. PMID: 23171045
Open tubular columns containing the immobilized ligand binding domain of peroxisome proliferator-activated receptors α and γ for dual agonists characterization by frontal affinity chromatography with mass spectrometry detection.
Temporini C, Pochetti G, Fracchiolla G, Piemontese L, Montanari R, Moaddel R, Laghezza A, Altieri F, Cervoni L, Ubiali D, Prada E, Loiodice F, Massolini G, Calleri E. Temporini C, et al. Among authors: montanari r. J Chromatogr A. 2013 Apr 5;1284:36-43. doi: 10.1016/j.chroma.2013.01.077. Epub 2013 Feb 16. J Chromatogr A. 2013. PMID: 23466198 Free PMC article.
Resveratrol and its metabolites bind to PPARs.
Calleri E, Pochetti G, Dossou KSS, Laghezza A, Montanari R, Capelli D, Prada E, Loiodice F, Massolini G, Bernier M, Moaddel R. Calleri E, et al. Among authors: montanari r. Chembiochem. 2014 May 26;15(8):1154-1160. doi: 10.1002/cbic.201300754. Epub 2014 May 5. Chembiochem. 2014. PMID: 24796862 Free PMC article.
Structural basis of the transactivation deficiency of the human PPARγ F360L mutant associated with familial partial lipodystrophy.
Lori C, Pasquo A, Montanari R, Capelli D, Consalvi V, Chiaraluce R, Cervoni L, Loiodice F, Laghezza A, Aschi M, Giorgi A, Pochetti G. Lori C, et al. Among authors: montanari r. Acta Crystallogr D Biol Crystallogr. 2014 Jul;70(Pt 7):1965-76. doi: 10.1107/S1399004714009638. Epub 2014 Jun 29. Acta Crystallogr D Biol Crystallogr. 2014. PMID: 25004973
96 results