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Page 1
Single nuclei RNA-seq reveals a medium spiny neuron glutamate excitotoxicity signature prior to the onset of neuronal death in an ovine Huntington's disease model.
Jiang A, You L, Handley RR, Hawkins V, Reid SJ, Jacobsen JC, Patassini S, Rudiger SR, Mclaughlan CJ, Kelly JM, Verma PJ, Bawden CS, Gusella JF, MacDonald ME, Waldvogel HJ, Faull RLM, Lehnert K, Snell RG. Jiang A, et al. Among authors: verma pj. Hum Mol Genet. 2024 Aug 18;33(17):1524-1539. doi: 10.1093/hmg/ddae087. Hum Mol Genet. 2024. PMID: 38776957 Free PMC article.
Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
Handley RR, Reid SJ, Brauning R, Maclean P, Mears ER, Fourie I, Patassini S, Cooper GJS, Rudiger SR, McLaughlan CJ, Verma PJ, Gusella JF, MacDonald ME, Waldvogel HJ, Bawden CS, Faull RLM, Snell RG. Handley RR, et al. Among authors: verma pj. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11293-E11302. doi: 10.1073/pnas.1711243115. Epub 2017 Dec 11. Proc Natl Acad Sci U S A. 2017. PMID: 29229845 Free PMC article.
A Multi-Omic Huntington's Disease Transgenic Sheep-Model Database for Investigating Disease Pathogenesis.
Mears ER, Handley RR, Grant MJ, Reid SJ, Day BT, Rudiger SR, McLaughlan CJ, Verma PJ, Bawden SC, Patassini S, Unwin RD, Cooper GJS, Gusella JF, MacDonald ME, Brauning R, Maclean P, Pearson JF, Waldvogel HJ, Faull RLM, Snell RG. Mears ER, et al. Among authors: verma pj. J Huntingtons Dis. 2021;10(4):423-434. doi: 10.3233/JHD-210482. J Huntingtons Dis. 2021. PMID: 34420978 Free PMC article.
Alzheimer's disease markers in the aged sheep (Ovis aries).
Reid SJ, Mckean NE, Henty K, Portelius E, Blennow K, Rudiger SR, Bawden CS, Handley RR, Verma PJ, Faull RLM, Waldvogel HJ, Zetterberg H, Snell RG. Reid SJ, et al. Among authors: verma pj. Neurobiol Aging. 2017 Oct;58:112-119. doi: 10.1016/j.neurobiolaging.2017.06.020. Epub 2017 Jun 24. Neurobiol Aging. 2017. PMID: 28728117
Evaluation of miRNA as Biomarkers of Emotional Valence in Pigs.
Marsh L, Hutchinson MR, McLaughlan C, Musolino ST, Hebart ML, Terry R, Verma PJ, Hiendleder S, Whittaker AL. Marsh L, et al. Among authors: verma pj. Animals (Basel). 2021 Jul 9;11(7):2054. doi: 10.3390/ani11072054. Animals (Basel). 2021. PMID: 34359180 Free PMC article.
Mitochondrial DNA Depletion in Granulosa Cell Derived Nuclear Transfer Tissues.
Bebbere D, Ulbrich SE, Giller K, Zakhartchenko V, Reichenbach HD, Reichenbach M, Verma PJ, Wolf E, Ledda S, Hiendleder S. Bebbere D, et al. Among authors: verma pj. Front Cell Dev Biol. 2021 May 14;9:664099. doi: 10.3389/fcell.2021.664099. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34124044 Free PMC article.
Generating a Heat-Tolerance Mouse Model.
Liu J, Verma PJ. Liu J, et al. Among authors: verma pj. Methods Mol Biol. 2022;2495:259-272. doi: 10.1007/978-1-0716-2301-5_14. Methods Mol Biol. 2022. PMID: 35696038
Tools for Efficient Genome Editing; ZFN, TALEN, and CRISPR.
Shamshirgaran Y, Liu J, Sumer H, Verma PJ, Taheri-Ghahfarokhi A. Shamshirgaran Y, et al. Among authors: verma pj. Methods Mol Biol. 2022;2495:29-46. doi: 10.1007/978-1-0716-2301-5_2. Methods Mol Biol. 2022. PMID: 35696026 Review.
67 results