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Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep long-read RNA-seq.
Aguzzoli Heberle B, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Aguzzoli Heberle B, et al. Among authors: brandon ja. Nat Biotechnol. 2024 May 22. doi: 10.1038/s41587-024-02245-9. Online ahead of print. Nat Biotechnol. 2024. PMID: 38778214
Using deep long-read RNAseq in Alzheimer's disease brain to assess medical relevance of RNA isoform diversity.
Heberle BA, Brandon JA, Page ML, Nations KA, Dikobe KI, White BJ, Gordon LA, Fox GA, Wadsworth ME, Doyle PH, Williams BA, Fox EJ, Shantaraman A, Ryten M, Goodwin S, Ghiban E, Wappel R, Mavruk-Eskipehlivan S, Miller JB, Seyfried NT, Nelson PT, Fryer JD, Ebbert MTW. Heberle BA, et al. Among authors: brandon ja. bioRxiv [Preprint]. 2023 Dec 11:2023.08.06.552162. doi: 10.1101/2023.08.06.552162. bioRxiv. 2023. Update in: Nat Biotechnol. 2024 May 22. doi: 10.1038/s41587-024-02245-9 PMID: 37609156 Free PMC article. Updated. Preprint.
GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia.
Shade LMP, Katsumata Y, Abner EL, Aung KZ, Claas SA, Qiao Q, Heberle BA, Brandon JA, Page ML, Hohman TJ, Mukherjee S, Mayeux RP, Farrer LA, Schellenberg GD, Haines JL, Kukull WA, Nho K, Saykin AJ, Bennett DA, Schneider JA; National Alzheimer’s Coordinating Center; Ebbert MTW, Nelson PT, Fardo DW. Shade LMP, et al. Among authors: brandon ja. Nat Genet. 2024 Nov;56(11):2407-2421. doi: 10.1038/s41588-024-01939-9. Epub 2024 Oct 8. Nat Genet. 2024. PMID: 39379761 Free PMC article.
Magnetic Resonance Imaging of Macrophage Response to Radiation Therapy.
Yang H, Howerton B, Brown L, Izumi T, Cheek D, Brandon JA, Marti F, Gedaly R, Adatorwovor R, Chapelin F. Yang H, et al. Among authors: brandon ja. Cancers (Basel). 2023 Dec 17;15(24):5874. doi: 10.3390/cancers15245874. Cancers (Basel). 2023. PMID: 38136418 Free PMC article.
Rapid analysis of S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) isotopologues in stable isotope-resolved metabolomics (SIRM) using direct infusion nanoelectrospray ultra-high-resolution Fourier transform mass spectrometry (DI-nESI-UHR-FTMS).
Yang J, Fan TWM, Brandon JA, Lane AN, Higashi RM. Yang J, et al. Among authors: brandon ja. Anal Chim Acta. 2021 Oct 9;1181:338873. doi: 10.1016/j.aca.2021.338873. Epub 2021 Jul 26. Anal Chim Acta. 2021. PMID: 34556237 Free PMC article.
APOΕ4 lowers energy expenditure in females and impairs glucose oxidation by increasing flux through aerobic glycolysis.
Farmer BC, Williams HC, Devanney NA, Piron MA, Nation GK, Carter DJ, Walsh AE, Khanal R, Young LEA, Kluemper JC, Hernandez G, Allenger EJ, Mooney R, Golden LR, Smith CT, Brandon JA, Gupta VA, Kern PA, Gentry MS, Morganti JM, Sun RC, Johnson LA. Farmer BC, et al. Among authors: brandon ja. Mol Neurodegener. 2021 Sep 6;16(1):62. doi: 10.1186/s13024-021-00483-y. Mol Neurodegener. 2021. PMID: 34488832 Free PMC article.
33 results