Brown JA - Search Results

1

Rescue of impaired blood-brain barrier in tuberous sclerosis complex patient derived neurovascular unit.

Brown JA, Faley SL, Judge M, Ward P, Ihrie RA, Carson R, Armstrong L, Sahin M, Wikswo JP, Ess KC, Neely MD. Brown JA, et al. J Neurodev Disord. 2024 May 23;16(1):27. doi: 10.1186/s11689-024-09543-y. J Neurodev Disord. 2024. PMID: 38783199 Free PMC article.

2

Advances in blood-brain barrier modeling in microphysiological systems highlight critical differences in opioid transport due to cortisol exposure.

Brown JA, Faley SL, Shi Y, Hillgren KM, Sawada GA, Baker TK, Wikswo JP, Lippmann ES. Brown JA, et al. Fluids Barriers CNS. 2020 Jun 3;17(1):38. doi: 10.1186/s12987-020-00200-9. Fluids Barriers CNS. 2020. PMID: 32493346 Free PMC article.

3

Recreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor.

Brown JA, Pensabene V, Markov DA, Allwardt V, Neely MD, Shi M, Britt CM, Hoilett OS, Yang Q, Brewer BM, Samson PC, McCawley LJ, May JM, Webb DJ, Li D, Bowman AB, Reiserer RS, Wikswo JP. Brown JA, et al. Biomicrofluidics. 2015 Oct 26;9(5):054124. doi: 10.1063/1.4934713. eCollection 2015 Sep. Biomicrofluidics. 2015. PMID: 26576206 Free PMC article.

4

Metabolic consequences of inflammatory disruption of the blood-brain barrier in an organ-on-chip model of the human neurovascular unit.

Brown JA, Codreanu SG, Shi M, Sherrod SD, Markov DA, Neely MD, Britt CM, Hoilett OS, Reiserer RS, Samson PC, McCawley LJ, Webb DJ, Bowman AB, McLean JA, Wikswo JP. Brown JA, et al. J Neuroinflammation. 2016 Dec 12;13(1):306. doi: 10.1186/s12974-016-0760-y. J Neuroinflammation. 2016. PMID: 27955696 Free PMC article.

5

Application of a Human Blood Brain Barrier Organ-on-a-Chip Model to Evaluate Small Molecule Effectiveness against Venezuelan Equine Encephalitis Virus.

Boghdeh NA, Risner KH, Barrera MD, Britt CM, Schaffer DK, Alem F, Brown JA, Wikswo JP, Narayanan A. Boghdeh NA, et al. Among authors: brown ja. Viruses. 2022 Dec 15;14(12):2799. doi: 10.3390/v14122799. Viruses. 2022. PMID: 36560802 Free PMC article.

6

Gravity-perfused airway-on-a-chip optimized for quantitative BSL-3 studies of SARS-CoV-2 infection: barrier permeability, cytokine production, immunohistochemistry, and viral load assays.

Faley SL, Boghdeh NA, Schaffer DK, Spivey EC, Alem F, Narayanan A, Wikswo JP, Brown JA. Faley SL, et al. Among authors: brown ja. Lab Chip. 2024 Mar 12;24(6):1794-1807. doi: 10.1039/d3lc00894k. Lab Chip. 2024. PMID: 38362777 Free PMC article.

7

Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.

Vernetti L, Gough A, Baetz N, Blutt S, Broughman JR, Brown JA, Foulke-Abel J, Hasan N, In J, Kelly E, Kovbasnjuk O, Repper J, Senutovitch N, Stabb J, Yeung C, Zachos NC, Donowitz M, Estes M, Himmelfarb J, Truskey G, Wikswo JP, Taylor DL. Vernetti L, et al. Among authors: brown ja. Sci Rep. 2017 Feb 8;7:42296. doi: 10.1038/srep42296. Sci Rep. 2017. PMID: 28176881 Free PMC article.

8

The Microbiome and the Gut-Liver-Brain Axis for Central Nervous System Clinical Pharmacology: Challenges in Specifying and Integrating In Vitro and In Silico Models.

Hawkins KG, Casolaro C, Brown JA, Edwards DA, Wikswo JP. Hawkins KG, et al. Among authors: brown ja. Clin Pharmacol Ther. 2020 Nov;108(5):929-948. doi: 10.1002/cpt.1870. Epub 2020 May 29. Clin Pharmacol Ther. 2020. PMID: 32347548 Free PMC article. Review.

9

Metabolic consequences of interleukin-6 challenge in developing neurons and astroglia.

Brown JA, Sherrod SD, Goodwin CR, Brewer B, Yang L, Garbett KA, Li D, McLean JA, Wikswo JP, Mirnics K. Brown JA, et al. J Neuroinflammation. 2014 Nov 6;11:183. doi: 10.1186/s12974-014-0183-6. J Neuroinflammation. 2014. PMID: 25374324 Free PMC article.

10

Predicting susceptibility to SARS-CoV-2 infection based on structural differences in ACE2 across species.

Alexander MR, Schoeder CT, Brown JA, Smart CD, Moth C, Wikswo JP, Capra JA, Meiler J, Chen W, Madhur MS. Alexander MR, et al. Among authors: brown ja. FASEB J. 2020 Dec;34(12):15946-15960. doi: 10.1096/fj.202001808R. Epub 2020 Oct 4. FASEB J. 2020. PMID: 33015868 Free PMC article.

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