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Disease-modifying rdHSV-CA8* non-opioid analgesic gene therapy treats chronic osteoarthritis pain by activating Kv7 voltage-gated potassium channels.
Zhuang GZ, Goins WF, Kandel MB, Marzulli M, Zhang M, Glorioso JC, Kang Y, Levitt AE, Sarantopoulos KD, Levitt RC. Zhuang GZ, et al. Among authors: kandel mb. Front Mol Neurosci. 2024 Jul 17;17:1416148. doi: 10.3389/fnmol.2024.1416148. eCollection 2024. Front Mol Neurosci. 2024. PMID: 39086927 Free PMC article.