Yang X - Search Results

1

Inhibition of bacterial RNA polymerase function and protein-protein interactions: a promising approach for next-generation antibacterial therapeutics.

Ye J, Kan CH, Yang X, Ma C. Ye J, et al. Among authors: yang x. RSC Med Chem. 2024 Mar 26;15(5):1471-1487. doi: 10.1039/d3md00690e. eCollection 2024 May 22. RSC Med Chem. 2024. PMID: 38784472 Review.

2

Inhibitors of bacterial transcription initiation complex formation.

Ma C, Yang X, Kandemir H, Mielczarek M, Johnston EB, Griffith R, Kumar N, Lewis PJ. Ma C, et al. Among authors: yang x. ACS Chem Biol. 2013 Sep 20;8(9):1972-80. doi: 10.1021/cb400231p. Epub 2013 Jul 5. ACS Chem Biol. 2013. PMID: 23751807

3

Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation.

Mielczarek M, Devakaram RV, Ma C, Yang X, Kandemir H, Purwono B, Black DS, Griffith R, Lewis PJ, Kumar N. Mielczarek M, et al. Among authors: yang x. Org Biomol Chem. 2014 May 14;12(18):2882-94. doi: 10.1039/c4ob00460d. Org Biomol Chem. 2014. PMID: 24668488

4

A vector system that allows simple generation of mutant Escherichia coli RNA polymerase.

Yang X, Ma C, Lewis P. Yang X, et al. Plasmid. 2014 Sep;75:37-41. doi: 10.1016/j.plasmid.2014.06.002. Epub 2014 Jun 30. Plasmid. 2014. PMID: 24992039

5

RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.

Ma C, Mobli M, Yang X, Keller AN, King GF, Lewis PJ. Ma C, et al. Among authors: yang x. Nucleic Acids Res. 2015 Mar 11;43(5):2829-40. doi: 10.1093/nar/gkv108. Epub 2015 Feb 17. Nucleic Acids Res. 2015. PMID: 25690895 Free PMC article.

6

Synthesis and biological activity of novel mono-indole and mono-benzofuran inhibitors of bacterial transcription initiation complex formation.

Mielczarek M, Thomas RV, Ma C, Kandemir H, Yang X, Bhadbhade M, Black DS, Griffith R, Lewis PJ, Kumar N. Mielczarek M, et al. Among authors: yang x. Bioorg Med Chem. 2015 Apr 15;23(8):1763-75. doi: 10.1016/j.bmc.2015.02.037. Epub 2015 Feb 25. Bioorg Med Chem. 2015. PMID: 25778767

7

Identification of inhibitors of bacterial RNA polymerase.

Yang X, Ma C, Lewis PJ. Yang X, et al. Methods. 2015 Sep 15;86:45-50. doi: 10.1016/j.ymeth.2015.05.005. Epub 2015 May 12. Methods. 2015. PMID: 25976836 Review.

8

Design, synthesis, nitric oxide release and antibacterial evaluation of novel nitrated ocotillol-type derivatives.

Bi Y, Yang X, Zhang T, Liu Z, Zhang X, Lu J, Cheng K, Xu J, Wang H, Lv G, Lewis PJ, Meng Q, Ma C. Bi Y, et al. Among authors: yang x. Eur J Med Chem. 2015 Aug 28;101:71-80. doi: 10.1016/j.ejmech.2015.06.021. Epub 2015 Jun 17. Eur J Med Chem. 2015. PMID: 26114813

9

Bacterial Transcription as a Target for Antibacterial Drug Development.

Ma C, Yang X, Lewis PJ. Ma C, et al. Among authors: yang x. Microbiol Mol Biol Rev. 2016 Jan 13;80(1):139-60. doi: 10.1128/MMBR.00055-15. Print 2016 Mar. Microbiol Mol Biol Rev. 2016. PMID: 26764017 Free PMC article. Review.

10

From indole to pyrrole, furan, thiophene and pyridine: Search for novel small molecule inhibitors of bacterial transcription initiation complex formation.

Thach O, Mielczarek M, Ma C, Kutty SK, Yang X, Black DS, Griffith R, Lewis PJ, Kumar N. Thach O, et al. Among authors: yang x. Bioorg Med Chem. 2016 Mar 15;24(6):1171-82. doi: 10.1016/j.bmc.2016.01.040. Epub 2016 Jan 21. Bioorg Med Chem. 2016. PMID: 26860928

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