Ye J - Search Results

1

Inhibition of bacterial RNA polymerase function and protein-protein interactions: a promising approach for next-generation antibacterial therapeutics.

Ye J, Kan CH, Yang X, Ma C. Ye J, et al. RSC Med Chem. 2024 Mar 26;15(5):1471-1487. doi: 10.1039/d3md00690e. eCollection 2024 May 22. RSC Med Chem. 2024. PMID: 38784472 Review.

2

Simple Method for Studying in Vitro Protein-Protein Interactions Based on Protein Complementation and Its Application in Drug Screening Targeting Bacterial Transcription.

Tsang TF, Qiu Y, Lin L, Ye J, Ma C, Yang X. Tsang TF, et al. Among authors: ye j. ACS Infect Dis. 2019 Apr 12;5(4):521-527. doi: 10.1021/acsinfecdis.9b00020. Epub 2019 Mar 6. ACS Infect Dis. 2019. PMID: 30834747

3

First-In-Class Inhibitors Targeting the Interaction between Bacterial RNA Polymerase and Sigma Initiation Factor Affect the Viability and Toxin Release of Streptococcus pneumoniae.

Ye J, Chu AJ, Lin L, Yang X, Ma C. Ye J, et al. Molecules. 2019 Aug 9;24(16):2902. doi: 10.3390/molecules24162902. Molecules. 2019. PMID: 31405060 Free PMC article.

4

Novel N-Substituted oseltamivir derivatives as potent influenza neuraminidase inhibitors: Design, synthesis, biological evaluation, ADME prediction and molecular docking studies.

Ye J, Yang X, Xu M, Chan PK, Ma C. Ye J, et al. Eur J Med Chem. 2019 Nov 15;182:111635. doi: 10.1016/j.ejmech.2019.111635. Epub 2019 Aug 22. Eur J Med Chem. 2019. PMID: 31493744

5

Discovery of Antibacterials That Inhibit Bacterial RNA Polymerase Interactions with Sigma Factors.

Ye J, Chu AJ, Harper R, Chan ST, Shek TL, Zhang Y, Ip M, Sambir M, Artsimovitch I, Zuo Z, Yang X, Ma C. Ye J, et al. J Med Chem. 2020 Jul 23;63(14):7695-7720. doi: 10.1021/acs.jmedchem.0c00520. Epub 2020 Jul 7. J Med Chem. 2020. PMID: 32633513 Free PMC article.

6

Benzyl and benzoyl benzoic acid inhibitors of bacterial RNA polymerase-sigma factor interaction.

Ye J, Chu AJ, Lin L, Chan ST, Harper R, Xiao M, Artsimovitch I, Zuo Z, Ma C, Yang X. Ye J, et al. Eur J Med Chem. 2020 Dec 15;208:112671. doi: 10.1016/j.ejmech.2020.112671. Epub 2020 Aug 18. Eur J Med Chem. 2020. PMID: 32920341 Free PMC article.

7

Design, Synthesis, Biological Evaluation and In Silico Studies of Pyrazole-Based NH₂-Acyl Oseltamivir Analogues as Potent Neuraminidase Inhibitors.

Ye J, Lin L, Xu J, Chan PK, Yang X, Ma C. Ye J, et al. Pharmaceuticals (Basel). 2021 Apr 16;14(4):371. doi: 10.3390/ph14040371. Pharmaceuticals (Basel). 2021. PMID: 33923858 Free PMC article.

8

Inhibition of Influenza Virus Replication by Oseltamivir Derivatives.

Chan RWY, Tao KP, Ye J, Lui KKY, Yang X, Ma C, Chan PKS. Chan RWY, et al. Among authors: ye j. Pathogens. 2022 Feb 11;11(2):237. doi: 10.3390/pathogens11020237. Pathogens. 2022. PMID: 35215179 Free PMC article.

9

QSAR, Docking, and Molecular Dynamics Simulation Studies of Sigmacidins as Antimicrobials against Streptococci.

Ye J, Yang X, Ma C. Ye J, et al. Int J Mol Sci. 2022 Apr 7;23(8):4085. doi: 10.3390/ijms23084085. Int J Mol Sci. 2022. PMID: 35456906 Free PMC article.

10

Ligand-Based Drug Design of Novel Antimicrobials against Staphylococcus aureus by Targeting Bacterial Transcription.

Ye J, Yang X, Ma C. Ye J, et al. Int J Mol Sci. 2022 Dec 25;24(1):339. doi: 10.3390/ijms24010339. Int J Mol Sci. 2022. PMID: 36613782 Free PMC article.

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