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Early defects in mucopolysaccharidosis type IIIC disrupt excitatory synaptic transmission.
Pará C, Bose P, Bruno L, Freemantle E, Taherzadeh M, Pan X, Han C, McPherson PS, Lacaille JC, Bonneil É, Thibault P, O'Leary C, Bigger B, Morales CR, Di Cristo G, Pshezhetsky AV. Pará C, et al. Among authors: pshezhetsky av. JCI Insight. 2021 Aug 9;6(15):e142073. doi: 10.1172/jci.insight.142073. JCI Insight. 2021. PMID: 34156977 Free PMC article.
The Janus-like role of neuraminidase isoenzymes in inflammation.
Howlader MA, Demina EP, Samarani S, Guo T, Caillon A, Ahmad A, Pshezhetsky AV, Cairo CW. Howlader MA, et al. Among authors: pshezhetsky av. FASEB J. 2022 May;36(5):e22285. doi: 10.1096/fj.202101218R. FASEB J. 2022. PMID: 35363389 Free PMC article.
Structure and mechanism of lysosome transmembrane acetylation by HGSNAT.
Xu R, Ning Y, Ren F, Gu C, Zhu Z, Pan X, Pshezhetsky AV, Ge J, Yu J. Xu R, et al. Among authors: pshezhetsky av. Nat Struct Mol Biol. 2024 Oct;31(10):1502-1508. doi: 10.1038/s41594-024-01315-5. Epub 2024 May 20. Nat Struct Mol Biol. 2024. PMID: 38769387
Neuraminidases 3 and 4 regulate neuronal function by catabolizing brain gangliosides.
Pan X, De Aragão CBP, Velasco-Martin JP, Priestman DA, Wu HY, Takahashi K, Yamaguchi K, Sturiale L, Garozzo D, Platt FM, Lamarche-Vane N, Morales CR, Miyagi T, Pshezhetsky AV. Pan X, et al. Among authors: pshezhetsky av. FASEB J. 2017 Aug;31(8):3467-3483. doi: 10.1096/fj.201601299R. Epub 2017 Apr 25. FASEB J. 2017. PMID: 28442549
Loss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1.
Katorcha E, Klimova N, Makarava N, Savtchenko R, Pan X, Annunziata I, Takahashi K, Miyagi T, Pshezhetsky AV, d'Azzo A, Baskakov IV. Katorcha E, et al. Among authors: pshezhetsky av. PLoS One. 2015 Nov 16;10(11):e0143218. doi: 10.1371/journal.pone.0143218. eCollection 2015. PLoS One. 2015. PMID: 26569607 Free PMC article.
125 results