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22 results

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Page 1
The Exon Junction Complex component EIF4A3 plays a splicing-linked oncogenic role in pancreatic ductal adenocarcinoma.
Blázquez-Encinas R, Alors-Pérez E, Moreno-Montilla MT, García-Vioque V, Sánchez-Frías ME, Mafficini A, López-Cánovas JL, Bousquet C, Gahete MD, Lawlor RT, Luque RM, Scarpa A, Arjona-Sánchez Á, Pedraza-Arevalo S, Ibáñez-Costa A, Castaño JP. Blázquez-Encinas R, et al. Among authors: alors perez e. Cancer Gene Ther. 2024 Nov;31(11):1646-1657. doi: 10.1038/s41417-024-00814-3. Epub 2024 Sep 4. Cancer Gene Ther. 2024. PMID: 39232176 Free PMC article.
Spliceosomic dysregulation in pancreatic cancer uncovers splicing factors PRPF8 and RBMX as novel candidate actionable targets.
Alors-Pérez E, Blázquez-Encinas R, Moreno-Montilla MT, García-Vioque V, Jiménez-Vacas JM, Mafficini A, González-Borja I, Luchini C, Sánchez-Hidalgo JM, Sánchez-Frías ME, Pedraza-Arevalo S, Romero-Ruiz A, Lawlor RT, Viúdez A, Gahete MD, Scarpa A, Arjona-Sánchez Á, Luque RM, Ibáñez-Costa A, Castaño JP. Alors-Pérez E, et al. Mol Oncol. 2024 Oct;18(10):2524-2540. doi: 10.1002/1878-0261.13658. Epub 2024 May 24. Mol Oncol. 2024. PMID: 38790138 Free PMC article.
Altered CELF4 splicing factor enhances pancreatic neuroendocrine tumors aggressiveness influencing mTOR and everolimus response.
Alors-Pérez E, Pedraza-Arevalo S, Blázquez-Encinas R, García-Vioque V, Agraz-Doblas A, Yubero-Serrano EM, Sánchez-Frías ME, Serrano-Blanch R, Gálvez-Moreno MÁ, Gracia-Navarro F, Gahete MD, Arjona-Sánchez Á, Luque RM, Ibáñez-Costa A, Castaño JP. Alors-Pérez E, et al. Mol Ther Nucleic Acids. 2023 Dec 5;35(1):102090. doi: 10.1016/j.omtn.2023.102090. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2023. PMID: 38187140 Free PMC article.
Altered splicing machinery in lung carcinoids unveils NOVA1, PRPF8 and SRSF10 as novel candidates to understand tumor biology and expand biomarker discovery.
Blázquez-Encinas R, García-Vioque V, Caro-Cuenca T, Moreno-Montilla MT, Mangili F, Alors-Pérez E, Ventura S, Herrera-Martínez AD, Moreno-Casado P, Calzado MA, Salvatierra Á, Gálvez-Moreno MA, Fernandez-Cuesta L, Foll M, Luque RM, Alcala N, Pedraza-Arevalo S, Ibáñez-Costa A, Castaño JP. Blázquez-Encinas R, et al. Among authors: alors perez e. J Transl Med. 2023 Dec 4;21(1):879. doi: 10.1186/s12967-023-04754-8. J Transl Med. 2023. PMID: 38049848 Free PMC article.
Cytokines and Lymphoid Populations as Potential Biomarkers in Locally and Borderline Pancreatic Adenocarcinoma.
González-Borja I, Viúdez A, Alors-Pérez E, Goñi S, Amat I, Ghanem I, Pazo-Cid R, Feliu J, Alonso L, López C, Arrazubi V, Gallego J, Pérez-Sanz J, Hernández-García I, Vera R, Castaño JP, Fernández-Irigoyen J. González-Borja I, et al. Among authors: alors perez e. Cancers (Basel). 2022 Dec 5;14(23):5993. doi: 10.3390/cancers14235993. Cancers (Basel). 2022. PMID: 36497475 Free PMC article.
Spliceosomal profiling identifies EIF4A3 as a novel oncogene in hepatocellular carcinoma acting through the modulation of FGFR4 splicing.
López-Cánovas JL, Hermán-Sánchez N, Moreno-Montilla MT, Del Rio-Moreno M, Alors-Perez E, Sánchez-Frias ME, Amado V, Ciria R, Briceño J, de la Mata M, Castaño JP, Rodriguez-Perálvarez M, Luque RM, Gahete MD. López-Cánovas JL, et al. Among authors: alors perez e. Clin Transl Med. 2022 Nov;12(11):e1102. doi: 10.1002/ctm2.1102. Clin Transl Med. 2022. PMID: 36419260 Free PMC article.
The uprise of RNA biology in neuroendocrine neoplasms: altered splicing and RNA species unveil translational opportunities.
Blázquez-Encinas R, Moreno-Montilla MT, García-Vioque V, Gracia-Navarro F, Alors-Pérez E, Pedraza-Arevalo S, Ibáñez-Costa A, Castaño JP. Blázquez-Encinas R, et al. Among authors: alors perez e. Rev Endocr Metab Disord. 2023 Apr;24(2):267-282. doi: 10.1007/s11154-022-09771-4. Epub 2022 Nov 24. Rev Endocr Metab Disord. 2023. PMID: 36418657 Free PMC article. Review.
Spliceosomic dysregulation unveils NOVA1 as a candidate actionable therapeutic target in pancreatic neuroendocrine tumors.
Pedraza-Arevalo S, Alors-Pérez E, Blázquez-Encinas R, Herrera-Martínez AD, Jiménez-Vacas JM, Fuentes-Fayos AC, Reyes Ó, Ventura S, Sánchez-Sánchez R, Ortega-Salas R, Serrano-Blanch R, Gálvez-Moreno MA, Gahete MD, Ibáñez-Costa A, Luque RM, Castaño JP. Pedraza-Arevalo S, et al. Among authors: alors perez e. Transl Res. 2023 Jan;251:63-73. doi: 10.1016/j.trsl.2022.07.005. Epub 2022 Jul 24. Transl Res. 2023. PMID: 35882361
22 results