Kamb A - Search Results

1

NOT gated T cells that selectively target EGFR and other widely expressed tumor antigens.

Oh J, Kirsh C, Hsin JP, Radecki KC, Zampieri A, Manry D, Ando Y, Miller S, Chan J, McLeod E, Cunningham KM, Wong LM, Xu H, Kamb A. Oh J, et al. Among authors: kamb a. iScience. 2024 May 7;27(6):109913. doi: 10.1016/j.isci.2024.109913. eCollection 2024 Jun 21. iScience. 2024. PMID: 38799557 Free PMC article.

2

High-throughput screen to identify and optimize NOT gate receptors for cell therapy.

Martire S, Wang X, McElvain M, Suryawanshi V, Gill T, DiAndreth B, Lee W, Riley TP, Xu H, Netirojjanakul C, Kamb A. Martire S, et al. Among authors: kamb a. Cytometry A. 2024 Oct;105(10):741-751. doi: 10.1002/cyto.a.24893. Epub 2024 Aug 17. Cytometry A. 2024. PMID: 39152710

3

HLA-A∗02-gated safety switch for cancer therapy has exquisite specificity for its allelic target antigen.

Mock JY, Winters A, Riley TP, Bruno R, Naradikian MS, Sharma S, Jette CA, Elshimali R, Gahrs C, Toledo-Warshaviak D, West AP Jr, Kamb A, Hamburger AE. Mock JY, et al. Among authors: kamb a. Mol Ther Oncolytics. 2022 Oct 4;27:157-166. doi: 10.1016/j.omto.2022.09.010. eCollection 2022 Dec 15. Mol Ther Oncolytics. 2022. PMID: 36381658 Free PMC article.

4

Geometric parameters that affect the behavior of logic-gated CAR T cells.

Partin AC, Bruno R, Shafaattalab S, Vander Mause E, Winters A, Daris M, Gahrs C, Jette CA, DiAndreth B, Sandberg ML, Hamburger AE, Kamb A, Riley TP. Partin AC, et al. Among authors: kamb a. Front Immunol. 2024 Jan 26;15:1304765. doi: 10.3389/fimmu.2024.1304765. eCollection 2024. Front Immunol. 2024. PMID: 38343543 Free PMC article.

5

Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity.

Tokatlian T, Asuelime GE, Naradikian MS, Mock JY, Daris ME, Martin AD, Toledo Warshaviak D, Kamb A, Hamburger AE. Tokatlian T, et al. Among authors: kamb a. Cancer Res Commun. 2022 Jan 28;2(1):58-65. doi: 10.1158/2767-9764.CRC-21-0165. eCollection 2022 Jan. Cancer Res Commun. 2022. PMID: 36860694 Free PMC article.

6

The Tmod cellular logic gate as a solution for tumor-selective immunotherapy.

DiAndreth B, Hamburger AE, Xu H, Kamb A. DiAndreth B, et al. Among authors: kamb a. Clin Immunol. 2022 Aug;241:109030. doi: 10.1016/j.clim.2022.109030. Epub 2022 May 11. Clin Immunol. 2022. PMID: 35561999 Free article. Review.

7

Robust In Vitro Pharmacology of Tmod, a Synthetic Dual-Signal Integrator for Cancer Cell Therapy.

Manry D, Bolanos K, DiAndreth B, Mock JY, Kamb A. Manry D, et al. Among authors: kamb a. Front Immunol. 2022 Mar 10;13:826747. doi: 10.3389/fimmu.2022.826747. eCollection 2022. Front Immunol. 2022. PMID: 35359952 Free PMC article.

8

A carcinoembryonic antigen-specific cell therapy selectively targets tumor cells with HLA loss of heterozygosity in vitro and in vivo.

Sandberg ML, Wang X, Martin AD, Nampe DP, Gabrelow GB, Li CZ, McElvain ME, Lee WH, Shafaattalab S, Martire S, Fisher FA, Ando Y, Liu E, Ju D, Wong LM, Xu H, Kamb A. Sandberg ML, et al. Among authors: kamb a. Sci Transl Med. 2022 Mar 2;14(634):eabm0306. doi: 10.1126/scitranslmed.abm0306. Epub 2022 Mar 2. Sci Transl Med. 2022. PMID: 35235342

9

Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells.

Tokatlian T, Asuelime GE, Mock JY, DiAndreth B, Sharma S, Toledo Warshaviak D, Daris ME, Bolanos K, Luna BL, Naradikian MS, Deshmukh K, Hamburger AE, Kamb A. Tokatlian T, et al. Among authors: kamb a. J Immunother Cancer. 2022 Jan;10(1):e003826. doi: 10.1136/jitc-2021-003826. J Immunother Cancer. 2022. PMID: 35091455 Free PMC article.

10

A rational approach to assess off-target reactivity of a dual-signal integrator for T cell therapy.

Wang X, Wong LM, McElvain ME, Martire S, Lee WH, Li CZ, Fisher FA, Maheshwari RL, Wu ML, Imun MC, Murad R, Toledo Warshaviak D, Yin J, Kamb A, Xu H. Wang X, et al. Among authors: kamb a. Toxicol Appl Pharmacol. 2022 Feb 15;437:115894. doi: 10.1016/j.taap.2022.115894. Epub 2022 Jan 25. Toxicol Appl Pharmacol. 2022. PMID: 35085592 Free article.

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