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Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis.
Sajiir H, Wong KY, Müller A, Keshvari S, Burr L, Aiello E, Mezza T, Giaccari A, Sebastiani G, Dotta F, Ramm GA, Macdonald GA, McGuckin MA, Prins JB, Hasnain SZ. Sajiir H, et al. Among authors: dotta f. Nat Commun. 2024 May 29;15(1):4527. doi: 10.1038/s41467-024-48320-2. Nat Commun. 2024. PMID: 38811550 Free PMC article.
Intra-islet insulin synthesis defects are associated with endoplasmic reticulum stress and loss of beta cell identity in human diabetes.
Brusco N, Sebastiani G, Di Giuseppe G, Licata G, Grieco GE, Fignani D, Nigi L, Formichi C, Aiello E, Auddino S, Quero G, Cefalo CMA, Cinti F, Mari A, Ferraro PM, Pontecorvi A, Alfieri S, Giaccari A, Dotta F, Mezza T. Brusco N, et al. Among authors: dotta f. Diabetologia. 2023 Feb;66(2):354-366. doi: 10.1007/s00125-022-05814-2. Epub 2022 Oct 25. Diabetologia. 2023. PMID: 36280617 Free PMC article.
The case for virus-induced type 1 diabetes.
Spagnuolo I, Patti A, Sebastiani G, Nigi L, Dotta F. Spagnuolo I, et al. Among authors: dotta f. Curr Opin Endocrinol Diabetes Obes. 2013 Aug;20(4):292-8. doi: 10.1097/MED.0b013e328362a7d7. Curr Opin Endocrinol Diabetes Obes. 2013. PMID: 23743646 Review.
Pancreatic Alpha-Cells Contribute Together With Beta-Cells to CXCL10 Expression in Type 1 Diabetes.
Nigi L, Brusco N, Grieco GE, Licata G, Krogvold L, Marselli L, Gysemans C, Overbergh L, Marchetti P, Mathieu C, Dahl Jørgensen K, Sebastiani G, Dotta F. Nigi L, et al. Among authors: dotta f. Front Endocrinol (Lausanne). 2020 Sep 15;11:630. doi: 10.3389/fendo.2020.00630. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 33042009 Free PMC article.
Increased Expression of Viral Sensor MDA5 in Pancreatic Islets and in Hormone-Negative Endocrine Cells in Recent Onset Type 1 Diabetic Donors.
Nigi L, Brusco N, Grieco GE, Fignani D, Licata G, Formichi C, Aiello E, Marselli L, Marchetti P, Krogvold L, Jorgensen KD, Sebastiani G, Dotta F. Nigi L, et al. Among authors: dotta f. Front Immunol. 2022 Mar 11;13:833141. doi: 10.3389/fimmu.2022.833141. eCollection 2022. Front Immunol. 2022. PMID: 35359976 Free PMC article.
290 results