Duffield AS - Search Results

1

Inhibition of NOTCH4 sensitizes FLT3/ITD acute myeloid leukemia cells to FLT3 tyrosine kinase inhibition.

Zhu R, Shirley CM, Chu SH, Li L, Nguyen BH, Seo J, Wu M, Seale T, Duffield AS, Staudt LM, Levis M, Hu Y, Small D. Zhu R, et al. Among authors: duffield as. Leukemia. 2024 Jul;38(7):1581-1591. doi: 10.1038/s41375-024-02292-w. Epub 2024 May 29. Leukemia. 2024. PMID: 38811818

2

DOCK2 interacts with FLT3 and modulates the survival of FLT3-expressing leukemia cells.

Wu M, Hamaker M, Li L, Small D, Duffield AS. Wu M, et al. Among authors: duffield as. Leukemia. 2017 Mar;31(3):688-696. doi: 10.1038/leu.2016.284. Epub 2016 Oct 17. Leukemia. 2017. PMID: 27748370 Free PMC article.

3

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3.

Nagai K, Hou L, Li L, Nguyen B, Seale T, Shirley C, Ma H, Levis M, Ghiaur G, Duffield A, Small D. Nagai K, et al. Oncotarget. 2018 Aug 31;9(68):32885-32899. doi: 10.18632/oncotarget.25972. eCollection 2018 Aug 31. Oncotarget. 2018. PMID: 30250637 Free PMC article.

4

FLT3 tyrosine kinase inhibitors synergize with BCL-2 inhibition to eliminate FLT3/ITD acute leukemia cells through BIM activation.

Zhu R, Li L, Nguyen B, Seo J, Wu M, Seale T, Levis M, Duffield A, Hu Y, Small D. Zhu R, et al. Signal Transduct Target Ther. 2021 May 24;6(1):186. doi: 10.1038/s41392-021-00578-4. Signal Transduct Target Ther. 2021. PMID: 34024909 Free PMC article.

5

Knock-in of a FLT3/ITD mutation cooperates with a NUP98-HOXD13 fusion to generate acute myeloid leukemia in a mouse model.

Greenblatt S, Li L, Slape C, Nguyen B, Novak R, Duffield A, Huso D, Desiderio S, Borowitz MJ, Aplan P, Small D. Greenblatt S, et al. Blood. 2012 Mar 22;119(12):2883-94. doi: 10.1182/blood-2011-10-382283. Epub 2012 Feb 8. Blood. 2012. PMID: 22323452 Free PMC article.

6

FLT3 kinase inhibitor TTT-3002 overcomes both activating and drug resistance mutations in FLT3 in acute myeloid leukemia.

Ma HS, Nguyen B, Duffield AS, Li L, Galanis A, Williams AB, Brown PA, Levis MJ, Leahy DJ, Small D. Ma HS, et al. Among authors: duffield as. Cancer Res. 2014 Sep 15;74(18):5206-17. doi: 10.1158/0008-5472.CAN-14-1028. Epub 2014 Jul 24. Cancer Res. 2014. PMID: 25060518 Free PMC article.

7

All-trans retinoic acid synergizes with FLT3 inhibition to eliminate FLT3/ITD+ leukemia stem cells in vitro and in vivo.

Ma HS, Greenblatt SM, Shirley CM, Duffield AS, Bruner JK, Li L, Nguyen B, Jung E, Aplan PD, Ghiaur G, Jones RJ, Small D. Ma HS, et al. Among authors: duffield as. Blood. 2016 Jun 9;127(23):2867-78. doi: 10.1182/blood-2015-05-646786. Epub 2016 Apr 21. Blood. 2016. PMID: 27103744 Free PMC article.

8

Dnmt3a deletion cooperates with the Flt3/ITD mutation to drive leukemogenesis in a murine model.

Poitras JL, Heiser D, Li L, Nguyen B, Nagai K, Duffield AS, Gamper C, Small D. Poitras JL, et al. Among authors: duffield as. Oncotarget. 2016 Oct 25;7(43):69124-69135. doi: 10.18632/oncotarget.11986. Oncotarget. 2016. PMID: 27636998 Free PMC article.

9

DOCK2: A novel FLT3/ITD leukemia drug target.

Wu M, Small D, Duffield AS. Wu M, et al. Among authors: duffield as. Oncotarget. 2017 Sep 30;8(51):88253-88254. doi: 10.18632/oncotarget.21390. eCollection 2017 Oct 24. Oncotarget. 2017. PMID: 29179430 Free PMC article. No abstract available.

10

FLT3-ITD cooperates with Rac1 to modulate the sensitivity of leukemic cells to chemotherapeutic agents via regulation of DNA repair pathways.

Wu M, Li L, Hamaker M, Small D, Duffield AS. Wu M, et al. Among authors: duffield as. Haematologica. 2019 Dec;104(12):2418-2428. doi: 10.3324/haematol.2018.208843. Epub 2019 Apr 11. Haematologica. 2019. PMID: 30975911 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

65 results

Search Page

Filters