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Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1α and affect bone marrow homeostasis in mice and humans.
Koenis DS, Medzikovic L, Vos M, Beldman TJ, van Loenen PB, van Tiel CM, Hamers AAJ, Otermin Rubio I, de Waard V, de Vries CJM. Koenis DS, et al. Among authors: de vries cjm, de waard v. J Biol Chem. 2018 Sep 28;293(39):15070-15083. doi: 10.1074/jbc.RA118.002720. Epub 2018 Aug 15. J Biol Chem. 2018. PMID: 30111591 Free PMC article.
Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity.
Kurakula K, Koenis DS, Herzik MA Jr, Liu Y, Craft JW Jr, van Loenen PB, Vos M, Tran MK, Versteeg HH, Goumans MTH, Ruf W, de Vries CJM, Şen M. Kurakula K, et al. Among authors: de vries cjm. Haematologica. 2018 Jun;103(6):1073-1082. doi: 10.3324/haematol.2017.183087. Epub 2018 Mar 15. Haematologica. 2018. PMID: 29545340 Free PMC article.
Nur77 protects against adverse cardiac remodelling by limiting neuropeptide Y signalling in the sympathoadrenal-cardiac axis.
Medzikovic L, van Roomen C, Baartscheer A, van Loenen PB, de Vos J, Bakker ENTP, Koenis DS, Damanafshan A, Creemers EE, Arkenbout EK, de Vries CJM, de Waard V. Medzikovic L, et al. Among authors: de vries cjm, de vos j, de waard v. Cardiovasc Res. 2018 Oct 1;114(12):1617-1628. doi: 10.1093/cvr/cvy125. Cardiovasc Res. 2018. PMID: 29850786
NR4A nuclear receptors are orphans but not lonesome.
Kurakula K, Koenis DS, van Tiel CM, de Vries CJ. Kurakula K, et al. Biochim Biophys Acta. 2014 Nov;1843(11):2543-2555. doi: 10.1016/j.bbamcr.2014.06.010. Epub 2014 Jun 27. Biochim Biophys Acta. 2014. PMID: 24975497 Free article. Review.
99 results