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Page 1
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens.
Reiner BC, Chehimi SN, Merkel R, Toikumo S, Berrettini WH, Kranzler HR, Sanchez-Roige S, Kember RL, Schmidt HD, Crist RC. Reiner BC, et al. Among authors: kranzler hr. bioRxiv [Preprint]. 2024 May 26:2024.05.26.595949. doi: 10.1101/2024.05.26.595949. bioRxiv. 2024. Update in: Sci Rep. 2024 Aug 6;14(1):18258. doi: 10.1038/s41598-024-69255-0 PMID: 38826289 Free PMC article. Updated. Preprint.
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes.
Toikumo S, Jennings MV, Pham BK, Lee H, Mallard TT, Bianchi SB, Meredith JJ, Vilar-Ribó L, Xu H, Hatoum AS, Johnson EC, Pazdernik V, Jinwala Z, Pakala SR, Leger BS, Niarchou M, Ehinmowo M; Penn Medicine BioBank, Million Veteran Program, PsycheMERGE Substance Use Disorder Workgroup; Jenkins GD, Batzler A, Pendegraft R, Palmer AA, Zhou H, Biernacka JM, Coombes BJ, Gelernter J, Xu K, Hancock DB, Cox NJ, Smoller JW, Davis LK, Justice AC, Kranzler HR, Kember RL, Sanchez-Roige S. Toikumo S, et al. Among authors: kranzler hr. medRxiv [Preprint]. 2023 Sep 18:2023.03.27.23287713. doi: 10.1101/2023.03.27.23287713. medRxiv. 2023. Update in: Nat Hum Behav. 2024 Jun;8(6):1177-1193. doi: 10.1038/s41562-024-01851-6 PMID: 37034728 Free PMC article. Updated. Preprint.
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits.
Hartwell EE, Jinwala Z, Milone J, Ramirez S, Gelernter J, Kranzler HR, Kember RL. Hartwell EE, et al. Among authors: kranzler hr. medRxiv [Preprint]. 2024 Jan 23:2024.01.22.24301615. doi: 10.1101/2024.01.22.24301615. medRxiv. 2024. Update in: Neuropsychopharmacology. 2024 Dec;49(13):1958-1967. doi: 10.1038/s41386-024-01922-2 PMID: 38343859 Free PMC article. Updated. Preprint.
Divergent gene expression patterns in alcohol and opioid use disorders lead to consistent alterations in functional networks within the Dorsolateral Prefrontal Cortex.
MacDonald M, Fonseca PAS, Johnson K, Murray EM, Kember RL, Kranzler H, Mayfield D, da Silva D. MacDonald M, et al. bioRxiv [Preprint]. 2024 May 1:2024.04.29.591734. doi: 10.1101/2024.04.29.591734. bioRxiv. 2024. Update in: Transl Psychiatry. 2024 Oct 14;14(1):437. doi: 10.1038/s41398-024-03143-z PMID: 38746311 Free PMC article. Updated. Preprint.
Multi-omic network analysis identifies dysregulated neurobiological pathways in opioid addiction.
Sullivan KA, Kainer D, Lane M, Cashman M, Miller JI, Garvin MR, Townsend A, Quach BC, Willis C, Kruse P, Gaddis NC, Mathur R, Corradin O, Maher BS, Scacheri PC, Sanchez-Roige S, Palmer AA, Troiani V, Chesler EJ, Kember RL, Kranzler HR, Justice AC, Xu K, Aouizerat BE, Hancock DB, Johnson EO, Jacobson DA; VA Million Veteran Program. Sullivan KA, et al. Among authors: kranzler hr. Biol Psychiatry. 2024 Nov 28:S0006-3223(24)01781-5. doi: 10.1016/j.biopsych.2024.11.013. Online ahead of print. Biol Psychiatry. 2024. PMID: 39615775
Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program.
Verma A, Huffman JE, Rodriguez A, Conery M, Liu M, Ho YL, Kim Y, Heise DA, Guare L, Panickan VA, Garcon H, Linares F, Costa L, Goethert I, Tipton R, Honerlaw J, Davies L, Whitbourne S, Cohen J, Posner DC, Sangar R, Murray M, Wang X, Dochtermann DR, Devineni P, Shi Y, Nandi TN, Assimes TL, Brunette CA, Carroll RJ, Clifford R, Duvall S, Gelernter J, Hung A, Iyengar SK, Joseph J, Kember R, Kranzler H, Levey D, Luoh SW, Merritt VC, Overstreet C, Deak JD, Grant SFA, Polimanti R, Roussos P, Sun YV, Venkatesh S, Voloudakis G, Justice A, Begoli E, Ramoni R, Tourassi G, Pyarajan S, Tsao PS, O'Donnell CJ, Muralidhar S, Moser J, Casas JP, Bick AG, Zhou W, Cai T, Voight BF, Cho K, Gaziano MJ, Madduri RK, Damrauer SM, Liao KP. Verma A, et al. medRxiv [Preprint]. 2023 Jun 29:2023.06.28.23291975. doi: 10.1101/2023.06.28.23291975. medRxiv. 2023. Update in: Science. 2024 Jul 19;385(6706):eadj1182. doi: 10.1126/science.adj1182 PMID: 37425708 Free PMC article. Updated. Preprint.
638 results