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Page 1
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: biroccio a. Nucleic Acids Res. 2014 Mar;42(5):2945-57. doi: 10.1093/nar/gkt1289. Epub 2013 Dec 11. Nucleic Acids Res. 2014. PMID: 24335081 Free PMC article.
Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance.
Zizza P, Cingolani C, Artuso S, Salvati E, Rizzo A, D'Angelo C, Porru M, Pagano B, Amato J, Randazzo A, Novellino E, Stoppacciaro A, Gilson E, Stassi G, Leonetti C, Biroccio A. Zizza P, et al. Among authors: biroccio a. Nucleic Acids Res. 2016 Feb 29;44(4):1579-90. doi: 10.1093/nar/gkv1122. Epub 2015 Oct 27. Nucleic Acids Res. 2016. PMID: 26511095 Free PMC article.
Insights into telomeric G-quadruplex DNA recognition by HMGB1 protein.
Amato J, Cerofolini L, Brancaccio D, Giuntini S, Iaccarino N, Zizza P, Iachettini S, Biroccio A, Novellino E, Rosato A, Fragai M, Luchinat C, Randazzo A, Pagano B. Amato J, et al. Among authors: biroccio a. Nucleic Acids Res. 2019 Oct 10;47(18):9950-9966. doi: 10.1093/nar/gkz727. Nucleic Acids Res. 2019. PMID: 31504744 Free PMC article.
Identification of novel interactors of human telomeric G-quadruplex DNA.
Pagano B, Margarucci L, Zizza P, Amato J, Iaccarino N, Cassiano C, Salvati E, Novellino E, Biroccio A, Casapullo A, Randazzo A. Pagano B, et al. Among authors: biroccio a. Chem Commun (Camb). 2015 Feb 18;51(14):2964-7. doi: 10.1039/c4cc07231f. Chem Commun (Camb). 2015. PMID: 25594748
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D'Angelo C, Porru M, Mondello C, Aiello A, Farsetti A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: biroccio a. Nucleic Acids Res. 2015 Feb 18;43(3):1759-69. doi: 10.1093/nar/gkv006. Epub 2015 Jan 23. Nucleic Acids Res. 2015. PMID: 25618850 Free PMC article.
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
Rizzo A, Iachettini S, Salvati E, Zizza P, Maresca C, D'Angelo C, Benarroch-Popivker D, Capolupo A, Del Gaudio F, Cosconati S, Di Maro S, Merlino F, Novellino E, Amoreo CA, Mottolese M, Sperduti I, Gilson E, Biroccio A. Rizzo A, et al. Among authors: biroccio a. Nucleic Acids Res. 2017 Feb 28;45(4):1820-1834. doi: 10.1093/nar/gkw1202. Nucleic Acids Res. 2017. PMID: 27923994 Free PMC article.
Tandem application of ligand-based virtual screening and G4-OAS assay to identify novel G-quadruplex-targeting chemotypes.
Musumeci D, Amato J, Zizza P, Platella C, Cosconati S, Cingolani C, Biroccio A, Novellino E, Randazzo A, Giancola C, Pagano B, Montesarchio D. Musumeci D, et al. Among authors: biroccio a. Biochim Biophys Acta Gen Subj. 2017 May;1861(5 Pt B):1341-1352. doi: 10.1016/j.bbagen.2017.01.024. Epub 2017 Jan 24. Biochim Biophys Acta Gen Subj. 2017. PMID: 28130159
125 results