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ATP-binding cassette family C member 1 constrains metabolic responses to high-fat diet in male mice.
Villalobos E, Miguelez-Crespo A, Morgan RA, Ivatt L, Paul M, Simpson JP, Homer NZM, Kurian D, Aguilar J, Kline RA, Wishart TM, Morton NM, Stimson RH, Andrew R, Walker BR, Nixon M. Villalobos E, et al. Among authors: morgan ra. J Endocrinol. 2024 Jul 3;262(2):e240024. doi: 10.1530/JOE-24-0024. Print 2024 Aug 1. J Endocrinol. 2024. PMID: 38829241 Free PMC article.
Carbonyl reductase 1 catalyzes 20β-reduction of glucocorticoids, modulating receptor activation and metabolic complications of obesity.
Morgan RA, Beck KR, Nixon M, Homer NZM, Crawford AA, Melchers D, Houtman R, Meijer OC, Stomby A, Anderson AJ, Upreti R, Stimson RH, Olsson T, Michoel T, Cohain A, Ruusalepp A, Schadt EE, Björkegren JLM, Andrew R, Kenyon CJ, Hadoke PWF, Odermatt A, Keen JA, Walker BR. Morgan RA, et al. Sci Rep. 2017 Sep 6;7(1):10633. doi: 10.1038/s41598-017-10410-1. Sci Rep. 2017. PMID: 28878267 Free PMC article.
Carbonyl reductase 1 amplifies glucocorticoid action in adipose tissue and impairs glucose tolerance in lean mice.
Bell RMB, Villalobos E, Nixon M, Miguelez-Crespo A, Murphy L, Fawkes A, Coutts A, Sharp MGF, Koerner MV, Allan E, Meijer OC, Houtman R, Odermatt A, Beck KR, Denham SG, Lee P, Homer NZM, Walker BR, Morgan RA. Bell RMB, et al. Among authors: morgan ra. Mol Metab. 2021 Jun;48:101225. doi: 10.1016/j.molmet.2021.101225. Epub 2021 Mar 27. Mol Metab. 2021. PMID: 33785425 Free PMC article.
Comparison of mechanisms of angiostasis caused by the anti-inflammatory steroid 5α-tetrahydrocorticosterone versus conventional glucocorticoids.
Abernethie AJ, Gastaldello A, Maltese G, Morgan RA, McInnes KJ, Small GR, Walker BR, Livingstone DE, Hadoke PW, Andrew R. Abernethie AJ, et al. Among authors: morgan ra. Eur J Pharmacol. 2022 Aug 15;929:175111. doi: 10.1016/j.ejphar.2022.175111. Epub 2022 Jun 20. Eur J Pharmacol. 2022. PMID: 35738450 Free article.
351 results