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Physiologically-based pharmacokinetic modeling of pantoprazole to evaluate the role of CYP2C19 genetic variation and obesity in the pediatric population.
Thompson EJ, Jeong A, Helfer VE, Shakhnovich V, Edginton A, Balevic SJ, James LP, Collier DN, Anand R, Gonzalez D; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee. Thompson EJ, et al. Among authors: edginton a. CPT Pharmacometrics Syst Pharmacol. 2024 Aug;13(8):1394-1408. doi: 10.1002/psp4.13167. Epub 2024 Jun 4. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 38837864 Free PMC article. Clinical Trial.
The effect of operational stressors on ibuprofen pharmacokinetics.
Boscarino C, Edginton AN, Peng H, Riggs KW, Szeitz A, Cheung B. Boscarino C, et al. Among authors: edginton an. Eur J Clin Pharmacol. 2013 Jan;69(1):31-41. doi: 10.1007/s00228-012-1307-5. Epub 2012 May 31. Eur J Clin Pharmacol. 2013. PMID: 22648280 Clinical Trial.
Terminal half-life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database.
Versloot O, Iserman E, Chelle P, Germini F, Edginton AN, Schutgens REG, Iorio A, Fischer K; Pharmacokinetic (PK) Expert Working Group of the International Prophylaxis Study Group (IPSG). Versloot O, et al. Among authors: edginton an. J Thromb Haemost. 2021 Aug;19(8):1896-1906. doi: 10.1111/jth.15395. Epub 2021 Jun 18. J Thromb Haemost. 2021. PMID: 34013558 Free PMC article.
Impact of Adopting Population Pharmacokinetics for Tailoring Prophylaxis in Haemophilia A Patients: A Historically Controlled Observational Study.
Stemberger M, Kallenbach F, Schmit E, McEneny-King A, Germini F, Yeung CHT, Edginton AN, von Mackensen S, Kurnik K, Iorio A. Stemberger M, et al. Among authors: edginton an. Thromb Haemost. 2019 Mar;119(3):368-376. doi: 10.1055/s-0039-1677700. Epub 2019 Jan 27. Thromb Haemost. 2019. PMID: 30685872 Free article.
Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death.
Lee EA, Angka L, Rota SG, Hanlon T, Mitchell A, Hurren R, Wang XM, Gronda M, Boyaci E, Bojko B, Minden M, Sriskanthadevan S, Datti A, Wrana JL, Edginton A, Pawliszyn J, Joseph JW, Quadrilatero J, Schimmer AD, Spagnuolo PA. Lee EA, et al. Among authors: edginton a. Cancer Res. 2015 Jun 15;75(12):2478-88. doi: 10.1158/0008-5472.CAN-14-2676. Cancer Res. 2015. PMID: 26077472
Comparative pharmacokinetics of two extended half-life FVIII concentrates (Eloctate and Adynovate) in adolescents with hemophilia A: Is there a difference?
Carcao MD, Chelle P, Clarke E, Kim L, Tiseo L, Morfini M, Hossain T, Rand ML, Brown C, Edginton AN, Lillicrap D, Iorio A, Blanchette VS. Carcao MD, et al. Among authors: edginton an. J Thromb Haemost. 2019 Jul;17(7):1085-1096. doi: 10.1111/jth.14469. Epub 2019 Jun 2. J Thromb Haemost. 2019. PMID: 31038793 Free article.
139 results