Letai A - Search Results

1

Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics.

Korell F, Olson ML, Salas-Benito D, Leick MB, Larson RC, Bouffard A, Silva H, Gasparetto A, Berger TR, Kann MC, Mergen M, Kienka T, Wehrli M, Haradhvala NJ, Bailey SR, Letai A, Maus MV. Korell F, et al. Among authors: letai a. Sci Transl Med. 2024 Jun 5;16(750):eadk7640. doi: 10.1126/scitranslmed.adk7640. Epub 2024 Jun 5. Sci Transl Med. 2024. PMID: 38838132

2

BH3 domains as BCL-2 inhibitors: prototype cancer therapeutics.

Letai A. Letai A. Expert Opin Biol Ther. 2003 Apr;3(2):293-304. doi: 10.1517/14712598.3.2.293. Expert Opin Biol Ther. 2003. PMID: 12662143

3

Antiapoptotic BCL-2 is required for maintenance of a model leukemia.

Letai A, Sorcinelli MD, Beard C, Korsmeyer SJ. Letai A, et al. Cancer Cell. 2004 Sep;6(3):241-9. doi: 10.1016/j.ccr.2004.07.011. Cancer Cell. 2004. PMID: 15380515 Free article.

4

BCL-2: found bound and drugged!

Letai A. Letai A. Trends Mol Med. 2005 Oct;11(10):442-4. doi: 10.1016/j.molmed.2005.08.007. Trends Mol Med. 2005. PMID: 16150641 Review.

5

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.

Certo M, Del Gaizo Moore V, Nishino M, Wei G, Korsmeyer S, Armstrong SA, Letai A. Certo M, et al. Among authors: letai a. Cancer Cell. 2006 May;9(5):351-65. doi: 10.1016/j.ccr.2006.03.027. Cancer Cell. 2006. PMID: 16697956 Free article.

6

BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia.

Del Gaizo Moore V, Schlis KD, Sallan SE, Armstrong SA, Letai A. Del Gaizo Moore V, et al. Among authors: letai a. Blood. 2008 Feb 15;111(4):2300-9. doi: 10.1182/blood-2007-06-098012. Epub 2007 Dec 4. Blood. 2008. PMID: 18056841 Free PMC article.

7

Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion.

Deng J, Shimamura T, Perera S, Carlson NE, Cai D, Shapiro GI, Wong KK, Letai A. Deng J, et al. Among authors: letai a. Cancer Res. 2007 Dec 15;67(24):11867-75. doi: 10.1158/0008-5472.CAN-07-1961. Cancer Res. 2007. PMID: 18089817

8

Regulation of Bcl-2 family proteins by posttranslational modifications.

Kutuk O, Letai A. Kutuk O, et al. Among authors: letai a. Curr Mol Med. 2008 Mar;8(2):102-18. doi: 10.2174/156652408783769599. Curr Mol Med. 2008. PMID: 18336291 Review.

9

Rational design of therapeutics targeting the BCL-2 family: are some cancer cells primed for death but waiting for a final push?

Del Gaizo Moore V, Letai A. Del Gaizo Moore V, et al. Among authors: letai a. Adv Exp Med Biol. 2008;615:159-75. doi: 10.1007/978-1-4020-6554-5_8. Adv Exp Med Biol. 2008. PMID: 18437895 Review.

10

Control of mitochondrial apoptosis by the Bcl-2 family.

Brunelle JK, Letai A. Brunelle JK, et al. Among authors: letai a. J Cell Sci. 2009 Feb 15;122(Pt 4):437-41. doi: 10.1242/jcs.031682. J Cell Sci. 2009. PMID: 19193868 Free PMC article. Review. No abstract available.

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