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Page 1
Glucagon-like peptide 1 receptor is a T cell-negative costimulatory molecule.
Ben Nasr M, Usuelli V, Dellepiane S, Seelam AJ, Fiorentino TV, D'Addio F, Fiorina E, Xu C, Xie Y, Balasubramanian HB, Castillo-Leon E, Loreggian L, Maestroni A, Assi E, Loretelli C, Abdelsalam A, El Essawy B, Uccella S, Pastore I, Lunati ME, Sabiu G, Petrazzuolo A, Ducci G, Sacco E, Centofanti L, Venturini M, Mazzucchelli S, Mattinzoli D, Ikehata M, Castellano G, Visner G, Kaifeng L, Lee KM, Wang Z, Corradi D, La Rosa S, Danese S, Yang J, Markmann JF, Zuccotti GV, Abdi R, Folli F, Fiorina P. Ben Nasr M, et al. Among authors: el essawy b. Cell Metab. 2024 Jun 4;36(6):1302-1319.e12. doi: 10.1016/j.cmet.2024.05.001. Cell Metab. 2024. PMID: 38838642
Co-transplantation of autologous MSCs delays islet allograft rejection and generates a local immunoprivileged site.
Ben Nasr M, Vergani A, Avruch J, Liu L, Kefaloyianni E, D'Addio F, Tezza S, Corradi D, Bassi R, Valderrama-Vasquez A, Usuelli V, Kim J, Azzi J, El Essawy B, Markmann J, Abdi R, Fiorina P. Ben Nasr M, et al. Among authors: el essawy b. Acta Diabetol. 2015 Oct;52(5):917-27. doi: 10.1007/s00592-015-0735-y. Epub 2015 Mar 27. Acta Diabetol. 2015. PMID: 25808641 Free PMC article.
Immunotherapy for type 1 diabetes.
Frumento D, Ben Nasr M, El Essawy B, D'Addio F, Zuccotti GV, Fiorina P. Frumento D, et al. Among authors: el essawy b. J Endocrinol Invest. 2017 Aug;40(8):803-814. doi: 10.1007/s40618-017-0641-y. Epub 2017 Mar 4. J Endocrinol Invest. 2017. PMID: 28260183 Review.
P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes.
D'Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, Bassi R, Tezza S, Dellepiane S, El Essawy B, Iascone M, Iacovoni A, Borgese L, Liu K, Visner G, Dhe-Paganon S, Corradi D, Abdi R, Starling RC, Folli F, Zuccotti GV, Sayegh MH, Heeger PS, Chandraker A, Grigioni F, Fiorina P. D'Addio F, et al. Among authors: el essawy b. J Clin Invest. 2018 Aug 1;128(8):3490-3503. doi: 10.1172/JCI94524. Epub 2018 Jul 16. J Clin Invest. 2018. PMID: 30010623 Free PMC article.
miR-21 antagonism reprograms macrophage metabolism and abrogates chronic allograft vasculopathy.
Usuelli V, Ben Nasr M, D'Addio F, Liu K, Vergani A, El Essawy B, Yang J, Assi E, Uehara M, Rossi C, Solini A, Capobianco A, Rigamonti E, Potena L, Venturini M, Sabatino M, Bottarelli L, Ammirati E, Frigerio M, Castillo-Leon E, Maestroni A, Azzoni C, Loretelli C, Joe Seelam A, Tai AK, Pastore I, Becchi G, Corradi D, Visner GA, Zuccotti GV, Chau NB, Abdi R, Pezzolesi MG, Fiorina P. Usuelli V, et al. Among authors: el essawy b. Am J Transplant. 2021 Oct;21(10):3280-3295. doi: 10.1111/ajt.16581. Epub 2021 May 3. Am J Transplant. 2021. PMID: 33764625 Free PMC article.
The IL-8-CXCR1/2 axis contributes to diabetic kidney disease.
Loretelli C, Rocchio F, D'Addio F, Ben Nasr M, Castillo-Leon E, Dellepiane S, Vergani A, Abdelsalam A, Assi E, Maestroni A, Usuelli V, Bassi R, Pastore I, Yang J, El Essawy B, Elased KM, Fadini GP, Ippolito E, Seelam AJ, Pezzolesi M, Corradi D, Zuccotti GV, Gallieni M, Allegretti M, Niewczas MA, Fiorina P. Loretelli C, et al. Among authors: el essawy b. Metabolism. 2021 Aug;121:154804. doi: 10.1016/j.metabol.2021.154804. Epub 2021 Jun 10. Metabolism. 2021. PMID: 34097917
PD-1 blockade counteracts post-COVID-19 immune abnormalities and stimulates the anti-SARS-CoV-2 immune response.
Loretelli C, Abdelsalam A, D'Addio F, Ben Nasr M, Assi E, Usuelli V, Maestroni A, Seelam AJ, Ippolito E, Di Maggio S, Loreggian L, Radovanovic D, Vanetti C, Yang J, El Essawy B, Rossi A, Pastore I, Montefusco L, Lunati ME, Bolla AM, Biasin M, Antinori S, Santus P, Riva A, Zuccotti GV, Galli M, Rusconi S, Fiorina P. Loretelli C, et al. Among authors: el essawy b. JCI Insight. 2021 Dec 22;6(24):e146701. doi: 10.1172/jci.insight.146701. JCI Insight. 2021. PMID: 34784300 Free PMC article.
The IGFBP3/TMEM219 pathway regulates beta cell homeostasis.
D'Addio F, Maestroni A, Assi E, Ben Nasr M, Amabile G, Usuelli V, Loretelli C, Bertuzzi F, Antonioli B, Cardarelli F, El Essawy B, Solini A, Gerling IC, Bianchi C, Becchi G, Mazzucchelli S, Corradi D, Fadini GP, Foschi D, Markmann JF, Orsi E, Škrha J Jr, Camboni MG, Abdi R, James Shapiro AM, Folli F, Ludvigsson J, Del Prato S, Zuccotti G, Fiorina P. D'Addio F, et al. Among authors: el essawy b. Nat Commun. 2022 Feb 3;13(1):684. doi: 10.1038/s41467-022-28360-2. Nat Commun. 2022. PMID: 35115561 Free PMC article.
The anti-inflammatory and immunological properties of GLP-1 Receptor Agonists.
Bendotti G, Montefusco L, Lunati ME, Usuelli V, Pastore I, Lazzaroni E, Assi E, Seelam AJ, El Essawy B, Jang J, Loretelli C, D'Addio F, Berra C, Ben Nasr M, Zuccotti G, Fiorina P. Bendotti G, et al. Among authors: el essawy b. Pharmacol Res. 2022 Aug;182:106320. doi: 10.1016/j.phrs.2022.106320. Epub 2022 Jun 20. Pharmacol Res. 2022. PMID: 35738455 Review.
eATP and autoimmune diabetes.
Loretelli C, Pastore I, Lunati ME, Abdelsalam A, Usuelli V, Assi E, Fiorina E, Loreggian L, Balasubramanian HB, Xie Y, Yang J, El Essawy B, Montefusco L, D'Addio F, Ben Nasr M, Fiorina P. Loretelli C, et al. Among authors: el essawy b. Pharmacol Res. 2023 Apr;190:106709. doi: 10.1016/j.phrs.2023.106709. Epub 2023 Feb 25. Pharmacol Res. 2023. PMID: 36842542 Free article. Review.
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