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Page 1
Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma.
Davies N, Francis T, Oldreive C, Azam M, Wilson J, Byrd PJ, Burley M, Sharma-Oates A, Keane P, Alatawi S, Higgs MR, Rudzki Z, Ibrahim M, Perry T, Agathanggelou A, Hewitt AM, Smith E, Bonifer C, O'Connor M, Forment JV, Murray PG, Fennell E, Kelly G, Chang C, Stewart GS, Stankovic T, Kwok M, Taylor AM. Davies N, et al. Among authors: agathanggelou a. Haematologica. 2024 Dec 1;109(12):3989-4006. doi: 10.3324/haematol.2023.284404. Haematologica. 2024. PMID: 38841800 Free PMC article.
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target.
Kennedy E, Coulter E, Halliwell E, Profitos-Peleja N, Walsby E, Clark B, Phillips EH, Burley TA, Mitchell S, Devereux S, Fegan CD, Jones CI, Johnston R, Chevassut T, Schulz R, Seiffert M, Agathanggelou A, Oldreive C, Davies N, Stankovic T, Liloglou T, Pepper C, Pepper AGS. Kennedy E, et al. Among authors: agathanggelou a. Blood. 2021 Jun 3;137(22):3064-3078. doi: 10.1182/blood.2020005964. Blood. 2021. PMID: 33512408 Free PMC article.
Derivatisation of parthenolide to address chemoresistant chronic lymphocytic leukaemia.
Li X, Payne DT, Ampolu B, Bland N, Brown JT, Dutton MJ, Fitton CA, Gulliver A, Hale L, Hamza D, Jones G, Lane R, Leach AG, Male L, Merisor EG, Morton MJ, Quy AS, Roberts R, Scarll R, Schulz-Utermoehl T, Stankovic T, Stevenson B, Fossey JS, Agathanggelou A. Li X, et al. Among authors: agathanggelou a. Medchemcomm. 2019 Aug 1;10(8):1379-1390. doi: 10.1039/c9md00297a. eCollection 2019 Aug 1. Medchemcomm. 2019. PMID: 32952998 Free PMC article.
Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.
Kwok M, Oldreive C, Rawstron AC, Goel A, Papatzikas G, Jones RE, Drennan S, Agathanggelou A, Sharma-Oates A, Evans P, Smith E, Dalal S, Mao J, Hollows R, Gordon N, Hamada M, Davies NJ, Parry H, Beggs AD, Munir T, Moreton P, Paneesha S, Pratt G, Taylor AMR, Forconi F, Baird DM, Cazier JB, Moss P, Hillmen P, Stankovic T. Kwok M, et al. Among authors: agathanggelou a. Blood. 2020 Feb 6;135(6):411-428. doi: 10.1182/blood.2019001262. Blood. 2020. PMID: 31794600 Free article.
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions.
Zimmermann M, Murina O, Reijns MAM, Agathanggelou A, Challis R, Tarnauskaitė Ž, Muir M, Fluteau A, Aregger M, McEwan A, Yuan W, Clarke M, Lambros MB, Paneesha S, Moss P, Chandrashekhar M, Angers S, Moffat J, Brunton VG, Hart T, de Bono J, Stankovic T, Jackson AP, Durocher D. Zimmermann M, et al. Among authors: agathanggelou a. Nature. 2018 Jul;559(7713):285-289. doi: 10.1038/s41586-018-0291-z. Epub 2018 Jul 4. Nature. 2018. PMID: 29973717 Free PMC article.
Degradation of a Novel DNA Damage Response Protein, Tankyrase 1 Binding Protein 1, following Adenovirus Infection.
Chalabi Hagkarim N, Ryan EL, Byrd PJ, Hollingworth R, Shimwell NJ, Agathanggelou A, Vavasseur M, Kolbe V, Speiseder T, Dobner T, Stewart GS, Grand RJ. Chalabi Hagkarim N, et al. Among authors: agathanggelou a. J Virol. 2018 May 29;92(12):e02034-17. doi: 10.1128/JVI.02034-17. Print 2018 Jun 15. J Virol. 2018. PMID: 29593045 Free PMC article.
50 results